Olaquindox

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Names

[ CAS No. ]:
23696-28-8

[ Name ]:
Olaquindox

[Synonym ]:
Bisergon
2-((2-Hydroxyethyl)carbamoyl)-3-methylquinoxaline 1,4-dioxide
MFCD00210341
3-methyl-1,4-dioxy-quinoxaline-2-carboxylic acid 2-hydroxy-ethylamide
EINECS 245-832-7
Olaguindox
Bayernox
Olachindox
Bayonox
Olaquindox

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
343.3ºC

[ Melting Point ]:
209°C (dec.)

[ Molecular Formula ]:
C12H13N3O4

[ Molecular Weight ]:
263.249

[ Flash Point ]:
>204.4ºC

[ Exact Mass ]:
263.090607

[ PSA ]:
100.25000

[ LogP ]:
-2.20

[ Index of Refraction ]:
1.651

[ Storage condition ]:
0-6°C

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VD1582000
CHEMICAL NAME :
2-Quinoxalinecarboxamide, N-(2-hydroxyethyl)-3-methyl-, 1,4-dioxide
CAS REGISTRY NUMBER :
23696-28-8
LAST UPDATED :
199612
DATA ITEMS CITED :
13
MOLECULAR FORMULA :
C12-H13-N3-O4
MOLECULAR WEIGHT :
263.28
WISWESSER LINE NOTATION :
T66 BN ENJ BO CVM2Q D1 EO

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1717 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
3316 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
4550 mg/kg/13W-I
TOXIC EFFECTS :
Liver - changes in liver weight Nutritional and Gross Metabolic - weight loss or decreased weight gain Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other transferases
TYPE OF TEST :
Micronucleus test
TYPE OF TEST :
Micronucleus test
TYPE OF TEST :
Cytogenetic analysis

MUTATION DATA

TYPE OF TEST :
Sister chromatid exchange
TEST SYSTEM :
Rodent - hamster Lung
DOSE/DURATION :
20 mg/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 139,199,1984

Safety Information

[ Symbol ]:

GHS07, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H334

[ Precautionary Statements ]:
P261-P342 + P311

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R22;R43

[ Safety Phrases ]:
S36/37

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
VD1582000

[ HS Code ]:
2933990090

Synthetic Route

Precursor & DownStream

Precursor

  • 2-(ETHOXYCARBONYL)-3-METHYLQUINOXALINEDIIUM-1,4-DIOLATE
  • Benzofuroxan
  • N-(2-Hydroxyethyl)-3-oxobutanamide

DownStream

  • N-(2-hydroxyethyl)-3-methyl-4-oxidoquinoxalin-4-ium-2-carboxamide
  • 2-methyl-3-[N-(2-hydroxyethyl)carbamoyl]quinoxalin 4-oxide

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

First detection of oqxAB in Salmonella spp. isolated from food.

Antimicrob. Agents Chemother. 57(1) , 658-60, (2013)

Food-borne salmonellosis is an important public health problem worldwide and the second leading cause of food-borne illnesses in Hong Kong. In this study, the prevalence and antimicrobial resistance o...

Reduction of carbadox mediated by reaction of Mn(III) with oxalic acid.

Environ. Sci. Technol. 47(3) , 1357-64, (2013)

Manganese(III) geocomponents are commonly found in the soil environment, yet their roles in many biogeochemical processes remain unknown. In this study, we demonstrated that Mn(III) generated from the...

Residue depletion and tissue-plasma correlation of methyl-3-quinoxaline-2-carboxylic acid after dietary administration of olaquindox in pigs.

J. Agric. Food Chem. 58(2) , 937-42, (2010)

A residue depletion study was performed to investigate the tissue kinetics and tissue-plasma correlation of methyl-3-quinoxaline-2-carboxylic acid (MQCA), the marker residue of olaquindox (OLA), in pi...


More Articles


Related Compounds

  • Olaquindox-d4
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • 1,1-Dimethylethyl N-[2-[[(1-bromocyclobutyl)carbonyl]amino]ethyl]carbamate
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide