2,4,6-trimethyl-2,4,6-tris(3,3,3-trifluoropropyl)-1,3,5,2,4,6-trioxatrisilinane

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Names

[ CAS No. ]:
2374-14-3

[ Name ]:
2,4,6-trimethyl-2,4,6-tris(3,3,3-trifluoropropyl)-1,3,5,2,4,6-trioxatrisilinane

[Synonym ]:
1,3,5-Tris(3,3,3-trifluoropropyl)-1,3,5-trimethylcyclotrisiloxane
MFCD00240602
Fluorosilicone cyclic trimer
Cyclotrisiloxane, 2,4,6-trimethyl-2,4,6-tris(3,3,3-trifluoropropyl)-
2,4,6-Trimethyl-2,4,6-tris(3,3,3-trifluoropropyl)-1,3,5,2,4,6-trioxatrisilinane
Silicone fluid
1,3,5-Tris[(3,3,3-trifluoropropyl)methyl]cyclotrisiloxane
EINECS 219-154-7
Fluorosilicone trimer
B071 CUT II

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
253.5±35.0 °C at 760 mmHg

[ Melting Point ]:
35°C

[ Molecular Formula ]:
C12H21F9O3Si3

[ Molecular Weight ]:
468.535

[ Flash Point ]:
107.1±25.9 °C

[ Exact Mass ]:
468.065491

[ PSA ]:
27.69000

[ LogP ]:
6.12300

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.381

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
GZ4818000
CHEMICAL NAME :
Cyclotrisiloxane, 2,4,6-trimethyl-2,4,6-tris(3,3,3-trifluoropropyl)-
CAS REGISTRY NUMBER :
2374-14-3
LAST UPDATED :
199806
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C12-H21-F9-O3-Si3
MOLECULAR WEIGHT :
468.60

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
4200 mg/kg/21D-I
TOXIC EFFECTS :
Liver - changes in liver weight Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - phosphatases
REFERENCE :
DCTODJ Drug and Chemical Toxicology. (Marcel Dekker, 270 Madison Ave., New York, NY 10016) V.1- 1977/78- Volume(issue)/page/year: 5,415,1982
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
2100 mg/kg/21D-C
TOXIC EFFECTS :
Cardiac - changes in heart weight Kidney, Ureter, Bladder - changes in bladder weight Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count)
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0539962 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Administration onto the skin
DOSE :
10500 mg/kg
SEX/DURATION :
male 21 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count) Reproductive - Fertility - male fertility index (e.g. # males impregnating females per # males exposed to fertile nonpregnant females) Reproductive - Effects on Newborn - other postnatal measures or effects
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0539962

Safety Information

[ Hazard Codes ]:
F: Flammable;

[ Risk Phrases ]:
R25;R36/37/38

[ Safety Phrases ]:
S26-S36/37/39-S45

[ RIDADR ]:
2811

[ RTECS ]:
GZ4818000

[ Packaging Group ]:
II

[ Hazard Class ]:
6.1

[ HS Code ]:
2903399090

Synthetic Route

Precursor & DownStream

Precursor

  • (3,3,3-Trifluoropropyl)Methyldichlorosilane

DownStream

Customs

[ HS Code ]: 2903399090

[ Summary ]:
2903399090. brominated,fluorinated or iodinated derivatives of acyclic hydrocarbons. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%


Related Compounds

  • N-[1-(4,7-dimethoxy-1,3-benzothiazol-2-yl)piperidin-3-yl]methanesulfonamide
  • 2,4-Dimethyl-7-{3-[(pyrazin-2-yloxy)methyl]piperidin-1-yl}-1,8-naphthyridine
  • 4,7-Dimethoxy-2-[3-(morpholine-4-carbonyl)azetidin-1-yl]-1,3-benzothiazole
  • 2-[4-(6-cyclobutylpyrimidin-4-yl)piperazin-1-yl]-6-(1-methyl-1H-pyrazol-4-yl)pyrazine
  • 2-{4-[3-(2-methoxyethyl)-1,2,4-thiadiazol-5-yl]piperazin-1-yl}-6-(1-methyl-1H-pyrazol-4-yl)pyrazine
  • 2-(1-methyl-1H-pyrazol-4-yl)-6-{4-[(2E)-3-phenylprop-2-en-1-yl]piperazin-1-yl}pyrazine
  • 4-Methoxy-2-{3-[(pyrazin-2-yloxy)methyl]piperidin-1-yl}-1,3-benzothiazole
  • 6-Bromo-2-{3-[(pyrazin-2-yloxy)methyl]piperidin-1-yl}quinazoline
  • 8-cyclopentyl-5-methyl-2-{3-[(pyrazin-2-yloxy)methyl]piperidin-1-yl}-7H,8H-pyrido[2,3-d]pyrimidin-7-one
  • 1-{7-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl}-4-{pyrazolo[1,5-a]pyrimidin-5-yloxy}piperidine
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