Benz[a]anthracene,8-methyl-

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Names

[ CAS No. ]:
2381-31-9

[ Name ]:
Benz[a]anthracene,8-methyl-

[Synonym ]:
AR-E36 8-METHYLBENZ(A)ANTHRACENE
8-methylbenzo[a]anthracene

Chemical & Physical Properties

[ Density]:
1.164g/cm3

[ Boiling Point ]:
449.4ºC at 760mmHg

[ Molecular Formula ]:
C19H14

[ Molecular Weight ]:
242.31400

[ Flash Point ]:
217.8ºC

[ Exact Mass ]:
242.11000

[ LogP ]:
5.45460

[ Vapour Pressure ]:
7.61E-08mmHg at 25°C

[ Index of Refraction ]:
1.748

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CX1750000
CHEMICAL NAME :
Benz(a)anthracene, 8-methyl-
CAS REGISTRY NUMBER :
2381-31-9
BEILSTEIN REFERENCE NO. :
2047765
LAST UPDATED :
199612
DATA ITEMS CITED :
8
MOLECULAR FORMULA :
C19-H14
MOLECULAR WEIGHT :
242.33
WISWESSER LINE NOTATION :
L D6 B666J H1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
18 mg/kg
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1250 mg/kg/52W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
200 mg/kg
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Tumorigenic - tumors at site of application
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
200 mg/kg
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - facilitates action of known carcinogen

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
20 ug/plate
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 36,4525,1976

Safety Information

[ HS Code ]:
2902909090

Synthetic Route

Precursor & DownStream

Precursor

  • (2,3-dimethyl-phenyl)-[1]naphthyl ketone
  • 8-methyl-9,10-dihydro-8H-benz[a]anthracen-11-one
  • 2,3-Dimethylbenzonitrile
  • 2,3-Dimethylaniline
  • (10,11-dihydro-benz[a]anthracen-8-yl)-acetic acid
  • 8-methyl-10,11-dihydro-9H-benzo[a]anthracen-8-ol
  • Hydrochloric acid
  • 8-methyl-5,6,9,10-tetrahydro-8H-benz[a]anthracen-11-one
  • acetic acid
  • Toluene

DownStream

Customs

[ HS Code ]: 2902909090

[ Summary ]:
2902909090 other aromatic hydrocarbons。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:2.0%。General tariff:30.0%


Related Compounds

  • Benz[a]anthracene-8,9-diol, 6-fluoro-8,9-dihydro-7-(hydroxymethyl)-12-methyl-, trans- (9CI)
  • Benz[a]anthracene-8,9-diol, 4-fluoro-8,9-dihydro-7-(hydroxymethyl)-12-methyl-, trans- (9CI)
  • Benz(a)anthracene,8,9,10,11-tetrahydro-10,11-dihydroxy-8,9-epoxy-7-methyl-,anti
  • Benz[a]anthracene,9-methyl-
  • Benz(a)anthracene-8,9-diol, 11-bromo-8,9,10,11-tetrahydro-, dibenzoate , (8alpha,9beta,11alpha)-
  • Benz(a)anthracene, 8-phenyl-
  • 3-(Difluoromethyl)-5-(trifluoromethoxy)pyridine-2,6-diamine
  • 2-Bromo-5-(difluoromethyl)-6-methylnicotinamide
  • 6-Amino-5-(difluoromethyl)-3-nitropicolinamide
  • 3-(Difluoromethyl)-4-(hydroxymethyl)-5-methylpicolinonitrile
  • 6-(Bromomethyl)-5-(difluoromethyl)-3-(trifluoromethoxy)pyridin-2-amine
  • 2,3-Dibromo-4-fluorobenzotrifluoride
  • 3-(4-(Difluoromethoxy)-2,3-difluorophenyl)acrylic acid
  • 6-Chloro-2-(difluoromethyl)-5-(trifluoromethoxy)nicotinic acid
  • 5-Chloro-4-(chloromethyl)-3-(difluoromethyl)pyridin-2-amine
  • 5-(Difluoromethyl)-3-hydroxy-6-(trifluoromethyl)picolinonitrile
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