Phenazinium,2-amino-8-(dimethylamino)-10-phenyl-, chloride (1:1)
Suppliers
Names
[ CAS No. ]:
2390-56-9
[ Name ]:
Phenazinium,2-amino-8-(dimethylamino)-10-phenyl-, chloride (1:1)
[Synonym ]:
3-amino-7-dimethylamino-5-phenyl-phenazinium,chloride
Safranine 8B
C.I. Basic Violet 5
Methylene Violet BN
Safranine Bluish
Safranine 6B
Methylene Violet 3RD
Safranin bluish
Dimethylphenosafranine
Basic Violet 5
Phenosafranine,dimethyl
Chemical & Physical Properties
[ Molecular Formula ]:
C20H19ClN4
[ Molecular Weight ]:
350.84500
[ Exact Mass ]:
350.13000
[ PSA ]:
46.03000
[ LogP ]:
0.89810
[ Vapour Pressure ]:
4.03E-11mmHg at 25°C
[ Index of Refraction ]:
1.663
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- SG1600500
- CHEMICAL NAME :
- Phenazinium, 3-amino-7-(dimethylamino)-5-phenyl-, chloride
- CAS REGISTRY NUMBER :
- 2390-56-9
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C20-H19-N4.Cl
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 46 mg/kg/4D-I
- TOXIC EFFECTS :
- Related to Chronic Data - death
- REFERENCE :
- BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 7,494,1952
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Primate - monkey
- DOSE/DURATION :
- 60 mg/kg/9D-I
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Related to Chronic Data - death
- REFERENCE :
- BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 7,494,1952
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 600 mg/kg/4D-I
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Behavioral - food intake (animal) Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis)
- REFERENCE :
- BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 7,494,1952
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 50 mg/kg/10D-I
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Behavioral - food intake (animal) Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis)
- REFERENCE :
- BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 7,494,1952
Safety Information
[ HS Code ]:
2933990090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933990090
[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%