o-Nicotine

Names

[ CAS No. ]:
23950-04-1

[ Name ]:
o-Nicotine

[Synonym ]:
1-methyl-2-pyrrolidinethanol
1-Methyl-2-pyrrolidine ethanol
2,2'-Nicotin

Chemical & Physical Properties

[ Density]:
1.032g/cm3

[ Boiling Point ]:
246ºC at 760mmHg

[ Molecular Formula ]:
C10H14N2

[ Molecular Weight ]:
162.23200

[ Flash Point ]:
102.6ºC

[ Exact Mass ]:
162.11600

[ PSA ]:
16.13000

[ LogP ]:
1.78620

[ Vapour Pressure ]:
0.0278mmHg at 25°C

[ Index of Refraction ]:
1.539

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UT5809000
CHEMICAL NAME :
Pyridine, 2-(1-methyl-2-pyrrolidinyl)-
CAS REGISTRY NUMBER :
23950-04-1
LAST UPDATED :
199012
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C10-H14-N2
MOLECULAR WEIGHT :
162.26

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
320 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85IXA4 "Structure et Activite Pharmacodyanmique des Medicaments du Systeme Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948 Volume(issue)/page/year: -,584,1948
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Amphibian - frog
DOSE/DURATION :
600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85IXA4 "Structure et Activite Pharmacodyanmique des Medicaments du Systeme Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948 Volume(issue)/page/year: -,584,1948

Safety Information

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Formaldehyde
  • 2-(2-Pyrrolidinyl)pyridine
  • Dimethyl sulfate
  • 1-Methylpyrrolidine
  • 2-Picolylamine
  • N-(pyridin-2-ylmethyl)formamide
  • N-Methyl-1-pyridin-2-ylmethanamine
  • 2-(methylcarbamoyl)-4-methylquinoline
  • 2-(1-methyl-1H-pyrrol-2-yl)pyridine

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • o-Nitrobenzyl-5 tetrahydro-5,6,7,7a 4H-thieno(3,2-c)pyridinone-2 oxala te [French]
  • O-(OCTYLPHOSPHORYL)CHOLINE SOLUTION
  • o-(3-Amino-4-sodiooxybenzoyl)benzoic acid sodium salt
  • O-butyl butoxycarbothioylsulfanylmethoxymethylsulfanylmethanethioate
  • O-Desmethyl apixaban
  • o-aminobutylbenzene
  • (1-((3-Chloropyrazin-2-yl)methyl)piperidin-4-yl)methanamine hydrochloride
  • 1-(1,4-Diazepan-1-yl)-2-(thiophen-3-yl)ethanone
  • N-(pyrrolidin-3-yl)-2-(thiophen-3-yl)acetamide hydrochloride
  • N-(pyrrolidin-3-ylmethyl)-2-(thiophen-3-yl)acetamide hydrochloride
  • (R)-2-(piperidin-3-ylamino)-1-(1H-pyrrol-2-yl)ethanone hydrochloride
  • [(2R,3R)-1-Benzyl-3-phenylazetidin-2-yl]methanol
  • Ethyl 2-(9,10-dihydrophenanthren-2-yl)acetate
  • (R)-1-(furan-2-yl)-2-(piperidin-3-ylamino)ethanone hydrochloride
  • (4S)-4-phenyl-2-(trifluoromethyl)-1,3-oxazolidine
  • 1-(2,4-Dibromo-6-methoxyphenyl)ethanone
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