o-Nicotine

Names

[ CAS No. ]:
23950-04-1

[ Name ]:
o-Nicotine

[Synonym ]:
1-methyl-2-pyrrolidinethanol
1-Methyl-2-pyrrolidine ethanol
2,2'-Nicotin

Chemical & Physical Properties

[ Density]:
1.032g/cm3

[ Boiling Point ]:
246ºC at 760mmHg

[ Molecular Formula ]:
C10H14N2

[ Molecular Weight ]:
162.23200

[ Flash Point ]:
102.6ºC

[ Exact Mass ]:
162.11600

[ PSA ]:
16.13000

[ LogP ]:
1.78620

[ Vapour Pressure ]:
0.0278mmHg at 25°C

[ Index of Refraction ]:
1.539

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UT5809000
CHEMICAL NAME :
Pyridine, 2-(1-methyl-2-pyrrolidinyl)-
CAS REGISTRY NUMBER :
23950-04-1
LAST UPDATED :
199012
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C10-H14-N2
MOLECULAR WEIGHT :
162.26

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
320 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85IXA4 "Structure et Activite Pharmacodyanmique des Medicaments du Systeme Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948 Volume(issue)/page/year: -,584,1948
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Amphibian - frog
DOSE/DURATION :
600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85IXA4 "Structure et Activite Pharmacodyanmique des Medicaments du Systeme Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948 Volume(issue)/page/year: -,584,1948

Safety Information

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Formaldehyde
  • 2-(2-Pyrrolidinyl)pyridine
  • Dimethyl sulfate
  • 1-Methylpyrrolidine
  • 2-Picolylamine
  • N-(pyridin-2-ylmethyl)formamide
  • N-Methyl-1-pyridin-2-ylmethanamine
  • 2-(methylcarbamoyl)-4-methylquinoline
  • 2-(1-methyl-1H-pyrrol-2-yl)pyridine

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • o-Nitrobenzyl-5 tetrahydro-5,6,7,7a 4H-thieno(3,2-c)pyridinone-2 oxala te [French]
  • O-(OCTYLPHOSPHORYL)CHOLINE SOLUTION
  • o-(3-Amino-4-sodiooxybenzoyl)benzoic acid sodium salt
  • O-butyl butoxycarbothioylsulfanylmethoxymethylsulfanylmethanethioate
  • O-Desmethyl apixaban
  • o-aminobutylbenzene
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-(3-Hydroxy-4-nitrophenyl)-3-methylbutanoic acid
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • (2R)-2-{2-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)oxan-3-yl]acetamido}propanoic acid
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • 5-[2-(Chloromethyl)-2-methylbut-3-en-1-yl]-1,2-thiazole
  • 4-{[(Benzyloxy)carbonyl]amino}-3-(2,3-dihydro-1-benzofuran-5-yl)butanoic acid
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide