2,6-Dichloropyridine

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Names

[ CAS No. ]:
2402-78-0

[ Name ]:
2,6-Dichloropyridine

[Synonym ]:
MFCD00006244
EINECS 219-282-3
2,6-Dichloropyridine
Pyridine, 2,6-dichloro-
2,6-Dichlor-pyridin
2,6-Cl2C5H3N
Pyridine,2,6-dichloro
2,5-DICHLOROANILINE
2,6-dichloro-pyridine

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
206.0±20.0 °C at 760 mmHg

[ Melting Point ]:
83-86 °C(lit.)

[ Molecular Formula ]:
C5H3Cl2N

[ Molecular Weight ]:
147.990

[ Flash Point ]:
97.5±7.4 °C

[ Exact Mass ]:
146.964249

[ PSA ]:
12.89000

[ LogP ]:
2.08

[ Vapour Pressure ]:
0.3±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.554

[ Water Solubility ]:
<1 g/L (20 ºC)

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
US8400000
CHEMICAL NAME :
Pyridine, 2,6-dichloro-
CAS REGISTRY NUMBER :
2402-78-0
BEILSTEIN REFERENCE NO. :
0108664
LAST UPDATED :
199712
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C5-H3-Cl2-N
MOLECULAR WEIGHT :
147.99
WISWESSER LINE NOTATION :
T6NJ BG FG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
176 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 33,825,1987
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
115 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - antipsychotic Liver - fatty liver degeneration
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 11,361,1967

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301

[ Precautionary Statements ]:
P301 + P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R22;R36/37/38

[ Safety Phrases ]:
S36/37/39-S45-S37/39-S26

[ RIDADR ]:
UN 2811 6.1/PG 2

[ WGK Germany ]:
3

[ RTECS ]:
US8400000

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-Chloropyridine
  • 2,6-Dichloropyridine 1-oxide
  • 2-Chloro-6-methoxypyridine
  • 2,6-Dibromopyridine
  • 3-Chlorostyrene
  • 4-Chlorostyrene
  • Benzene,(1E)-1-propen-1-yl-
  • phenylene-ethylene
  • 2-Chloro-6-ethoxypyridine
  • PYRIDINE, 2-CHLORO-6-(PHENYLMETHOXY)-

DownStream

  • 1-(6-ethoxypyridin-2-yl)piperazine
  • (6-Chloro-pyridin-2-yl)-dimethyl-amine
  • 6,6'-Dimethyl-2,2'-bipyridine
  • 2,6-bis(6-methylpyridin-2-yl)pyridine
  • 2,2'-Bipyridine
  • 6-Methyl-2,2':6',2''-terpyridine
  • 6-methyl-2,2'-bipyridine
  • 2,6-Diiodopyridine
  • 2-Chloro-iodopyridine

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • 2,6-DICHLOROPYRIDINE
  • 3-iodo-2,6-dichloropyridine
  • 2,6-DICHLOROPYRIDINE-4-THIOL
  • 2,6-Dichloropyridine 1-oxide
  • 2,6-DICHLOROPYRIDINE-1-OXIDE
  • 4-Bromo-2,6-dichloropyridine
  • N-(6-methylpyridin-2-yl)-5-(N-(3-(trifluoromethyl)phenyl)sulfamoyl)furan-2-carboxamide
  • 5-(N-(furan-2-ylmethyl)sulfamoyl)-N-(5-methyl-1,3,4-thiadiazol-2-yl)furan-2-carboxamide
  • 4-(1H-imidazol-1-yl)-6-(4-(mesitylsulfonyl)piperazin-1-yl)pyrimidine
  • 3-amino-N-(3-chloro-4-cyanophenyl)-4-methylbenzamide
  • N-(1,1-dioxidotetrahydro-3-thienyl)-N-methyl-2-[(6-oxo-7,8,9,10-tetrahydro-6H-benzo[c]chromen-3-yl)oxy]acetamide
  • N-(6-methylheptan-2-yl)-2-(6-oxo-3-phenylpyridazin-1(6H)-yl)acetamide
  • N-(1,3-dihydro-2H-benzimidazol-2-ylidene)-5-oxo-5-[4-(pyridin-2-yl)piperazin-1-yl]pentanamide
  • 3-Chloro-2-[(difluoromethyl)sulfanyl]aniline
  • N-(furan-2-ylmethyl)-2-(4-oxoquinazolin-3(4H)-yl)benzamide
  • ethyl 4-methyl-2-{[(1-methyl-1H-indol-2-yl)carbonyl]amino}-1,3-thiazole-5-carboxylate
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