Benzeneacetic acid, a-ethoxy-a-phenyl-, 2-(dimethylamino)ethylester, hydrochloride (9CI)

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Names

[ Name ]:
Benzeneacetic acid, a-ethoxy-a-phenyl-, 2-(dimethylamino)ethylester, hydrochloride (9CI)

[Synonym ]:
Aestocin
Aethoxy-diphenyl-essigsaeure-(2-dimethylamino-aethylester),Hydrochlorid
Propalgyl
Dimenoxadol hydrochloride
ethoxy-diphenyl-acetic acid-(2-dimethylamino-ethyl ester),hydrochloride
Estocin

Chemical & Physical Properties

[ Boiling Point ]:
444.5ºC at 760mmHg

[ Molecular Formula ]:
C₂₀H₂₆ClNO₃

[ Molecular Weight ]:
363.87800

[ Flash Point ]:
222.6ºC

[ Exact Mass ]:
363.16000

[ PSA ]:
38.77000

[ LogP ]:
3.87350

[ Vapour Pressure ]:
4.26E-08mmHg at 25°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AH2790000

CHEMICAL NAME :: Acetic acid, 2,2-diphenyl-2-ethoxy-, (2-(dimethylamino)ethyl) ester, hydrochloride

CAS REGISTRY NUMBER :: 2424-75-1

LAST UPDATED :: 199012

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C20-H25-N-O3.Cl-H

MOLECULAR WEIGHT :: 363.92

WISWESSER LINE NOTATION :: 2OXR&R&VO2N1&1 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 66 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 8,189,1974

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 175 mg/kg

TOXIC EFFECTS :: Behavioral - analgesia

REFERENCE :: PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 4,7,1970

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 179 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 32,317,1969

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 40 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 8,571,1965

Safety Information

[ HS Code ]:
2922199090

Customs

[ HS Code ]: 2922199090

[ Summary ]:
2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Related Compounds

4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
4-Fluoro-2-oxo-2,3-dihydrobenzo[d]oxazole-7-sulfonyl chloride
Tert-butyl-4-butoxyphenyl carbamate
(4-Methyl-tetrahydro-furan-2-yl)-methanol
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
N-(9-((2R,5S)-5-(Hydroxymethyl)-3-oxotetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-3H-purin-2-yl)isobutyramide
4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde