Boc-Glu-OtBu

Suppliers

Names

[ Name ]:
Boc-Glu-OtBu

[Synonym ]:
Boc-L-glutamicacid1-tert-butylester
Boc-L-glutamic acid 1-tert-butyl ester
MFCD00038273
N-(tert-Butoxycarbonyl)-L-glutamic Acid 1-tert-Butyl Ester
N-Boc-Glu-OtBu
N-(t-butoxycarbonyl)-L-glutamic acid t-butyl ester
Boc-Glu-Otbu
N-Boc-L-glutamic acid 1-tert-butyl ester
1-tert-Butyl N-(tert-Butoxycarbonyl)-L-glutamate
(S)-5-tert-butoxy-4-tert-butoxycarbonylamino-5-oxo-pentanoic acid
(4S)-5-[(2-Methyl-2-propanyl)oxy]-4-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)-5-oxopentanoic acid
5-[(2-Methyl-2-propanyl)oxy]-4-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)-5-oxopentanoic acid
(4S)-5-tert-Butoxy-4-[(tert-butoxycarbonyl)amino]-5-oxopentanoic acid (non-preferred name)
Glutamic acid, N-[(1,1-dimethylethoxy)carbonyl]-, 1-(1,1-dimethylethyl) ester
1-tert-Butyl N-Boc-L-glutamate
L-Glutamic acid, N-[(1,1-dimethylethoxy)carbonyl]-, 1-(1,1-dimethylethyl) ester

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
449.8±40.0 °C at 760 mmHg

[ Melting Point ]:
113 °C

[ Molecular Formula ]:
C₁₄H₂₅NO₆

[ Molecular Weight ]:
303.351

[ Flash Point ]:
225.8±27.3 °C

[ Exact Mass ]:
303.168182

[ PSA ]:
101.93000

[ LogP ]:
2.82

[ Vapour Pressure ]:
0.0±2.3 mmHg at 25°C

[ Index of Refraction ]:
1.470

[ Storage condition ]:
−20°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

(S)-1-tert-Butyl 5-methyl 2-((tert-butoxycarbonyl)amino)pentanedioate
Di-tert-butyl dicarbonate
N-(diphenylmethylene)-L-glutamic acid 1-(1,1-dimethylethyl) 5-benzyl ester
(S)-N-Boc-2-pyrrolidone-5-carboxylic acid tert-butyl ester
Boc-Glu(Bn)-tBu
L-glutamic acid
tert-Butyl 2-((diphenylmethylene)amino)acetate
Cbz-L-Glu(Ome)-OtBu
Boc-Glu(OMe)-OH
H-Glu(OBzl)-OH

DownStream

(S)-N-Boc-2-pyrrolidone-5-carboxylic acid tert-butyl ester
1,3-Dicyclohexylurea
(2S)-2-amino-5-[2-(2-hydroxyethylsulfanyl)ethoxy]-5-oxopentanoate
MNI-caged-L-glutamate
TERT-BUTYL 2-((TERT-BUTOXYCARBONYL)AMINO)-6-((METHYLSULFONYL)OXY)HEXANOATE
(4S)-4-amino-5-[[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy]-5-oxopentanoic acid
thioarginine
Boc-glu(osu)-otbu
5-Bromo-N-[(tert-butoxy)carbonyl]-L-norvaline tert-butyl ester

Articles

Folding graft copolymer with pendant drug segments for co-delivery of anticancer drugs.

Biomaterials 35(25) , 7194-203, (2014)

A graft copolymer with pendant drug segments can fold into nanostructures in a protein folding-like manner. The graft copolymer is constructed by directly polymerizing γ-camptothecin-glutamate N-carbo...