Erythromycin sulfamate

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Names

[ CAS No. ]:
24380-21-0

[ Name ]:
Erythromycin sulfamate

Chemical & Physical Properties

[ Boiling Point ]:
818.4ºC at 760 mmHg

[ Molecular Formula ]:
C37H70N2O16S

[ Molecular Weight ]:
831.02000

[ Flash Point ]:
448.8ºC

[ Exact Mass ]:
830.44500

[ PSA ]:
282.68000

[ LogP ]:
2.31460

[ Vapour Pressure ]:
4.94E-31mmHg at 25°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KF5796000
CHEMICAL NAME :
Erythromycin, sulfamate (salt)
CAS REGISTRY NUMBER :
24380-21-0
LAST UPDATED :
199201
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C37-H67-N-O13.H3-N-O3-S
MOLECULAR WEIGHT :
831.15
WISWESSER LINE NOTATION :
T-14-VO GVTJ C2 DQ D1 EQ F1 H1 JQ J1 L1 N1 KO- BT6OTJ CQ DN1&1 F1& MO- BT6OTJ DO1 D1 EQ &ZSWQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
127 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CMTRAG Chemotherapia. (Basel, Switzerland) V.1-12, 1960-67. For publisher information, see CHTHBK. Volume(issue)/page/year: 5,144,1962
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
480 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CMTRAG Chemotherapia. (Basel, Switzerland) V.1-12, 1960-67. For publisher information, see CHTHBK. Volume(issue)/page/year: 5,144,1962
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
217 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CMTRAG Chemotherapia. (Basel, Switzerland) V.1-12, 1960-67. For publisher information, see CHTHBK. Volume(issue)/page/year: 5,144,1962

Related Compounds

  • erythromycin-A, hydrochloride
  • 6-[4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-4-(5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl)oxy-3-(hydroxymethyl)-5,7,9,11,13-pentamethyl-oxacyclotetradecane-2,10-dione
  • erythromycin E
  • Erythromycin, 8,9-didehydro-N-demethyl-9-deoxo-6-deoxy-6,9-epoxy
  • Erythromycin, 14-hydroxy-6-O-methyl-
  • [4-(dimethylamino)-2-[[14-ethyl-7,12,13-trihydroxy-4-(5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl)oxy-3,5,7,9,11,13-hexamethyl-2,10-dioxo-oxacyclotetradec-6-yl]oxy]-6-methyloxan-3-yl] furan-2-carboxylate