Dapivirine (TMC120)

Suppliers

Names

[ Name ]:
Dapivirine (TMC120)

[Synonym ]:
4-{[4-(Mesitylamino)-2-pyrimidinyl]amino}benzonitrile
4-({4-[(2,4,6-trimethylphenyl)amino]pyrimidin-2-yl}amino)benzenecarbonitrile
Dapivirine (TMC120)
TMC120
Benzonitrile, 4-[[4-[(2,4,6-trimethylphenyl)amino]-2-pyrimidinyl]amino]-
R-147681
4-[[4-[(2,4,6-trimethylphenyl)amino]-2-pyrimidinyl]amino]benzonitrile
UNII: TCN4MG2VXS
Dapivirine
4-{[4-(Mesitylamino)pyrimidin-2-yl]amino}benzonitrile
UNII-TCN4MG2VXS
dapivirinum

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
557.9±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₀H₁₉N₅

[ Molecular Weight ]:
329.398

[ Flash Point ]:
291.2±32.9 °C

[ Exact Mass ]:
329.164032

[ PSA ]:
73.63000

[ LogP ]:
3.98

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.649

[ Storage condition ]:
-20°C

Safety Information

[ Hazard Codes ]:
Xi

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

4-Aminobenzonitrile
4-[(4,6-Dichloropyrimidin-2-yl)amino]benzonitrile
4-(4-chloro-6-(mesitylamino)pyrimidin-2-ylamino)benzonitrile

DownStream

Related Compounds

Dapivirine-d11
2-(Difluoromethyl)-3-methoxy-4-nitropyridine
2-(Difluoromethyl)-3-fluoro-5-hydroxypyridine-4-acetonitrile
2-(Difluoromethyl)-4-fluoro-5-iodopyridine-3-acetonitrile
2-(Difluoromethyl)-3-methyl-5-nitropyridine-6-acetonitrile
Pyridine, 2-(difluoromethoxy)-3-(2,4,5-trichlorophenyl)-6-(trifluoromethyl)-
2-(Difluoromethyl)-4-hydroxy-5-(trifluoromethyl)pyridine-3-acetonitrile
2-(Difluoromethyl)-4-hydroxypyridine-5-methanol
2-(Difluoromethyl)-3-hydroxy-4-nitropyridine-5-carboxaldehyde
2-(Difluoromethyl)-4-iodo-3-methoxypyridine-5-acetic acid
2-(Difluoromethyl)-4-iodo-6-methoxypyridine-3-carboxaldehyde

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.