3,5-Dichloropyridine

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Names

[ Name ]:
3,5-Dichloropyridine

[Synonym ]:
3,5-Dichlor-pyridin
3,5-dichlorpyridine
3,5-CHLOROPYRIDINE
Dichloropyridine
3,5-dichloropyridyl
Pyridine, 3,5-dichloro-
MFCD00006376
3,5-Dichloropyridine
3.5-Dichloropryidine
3,5-Dichloripyridine
3,5-dichloro-pyridin
3,5-Dichloroypyridine
EINECS 219-537-9
3,5-dichloro-pyridine
Etoricoxib Impurity 34

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
173.7±20.0 °C at 760 mmHg

[ Melting Point ]:
65-67°C

[ Molecular Formula ]:
C₅H₃Cl₂N

[ Molecular Weight ]:
147.99

[ Flash Point ]:
73.4±7.4 °C

[ Exact Mass ]:
146.964249

[ PSA ]:
12.89000

[ LogP ]:
2.42

[ Vapour Pressure ]:
1.7±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.554

[ Storage condition ]:
Refrigerator

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: US8575000

CHEMICAL NAME :: Pyridine, 3,5-dichloro-

CAS REGISTRY NUMBER :: 2457-47-8

BEILSTEIN REFERENCE NO. :: 0001973

LAST UPDATED :: 199712

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C5-H3-Cl2-N

MOLECULAR WEIGHT :: 147.99

WISWESSER LINE NOTATION :: T6NJ CG EG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1180 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - antipsychotic Liver - fatty liver degeneration

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 11,361,1967

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H315-H318-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R22;R37/38;R41

[ Safety Phrases ]:
S26-S39

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
US8575000

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

2,3,5-Trichloropyridine
Perchloropyridine
2,3,4,5-Tetrachloropyridine
2,3,5,6-Tetrachloropyridine
3,5-dichloro-4-pyridinecarboxaldehyde
Pyridine chlorhydrate
N-methyl-3,5-dichloropyridinium iodide
methyl iodide
(2R)-2-Methoxy-3,4-dihydro-2H-pyran
3,5-DICHLOROISONICOTINIC ACID

DownStream

3,5-Dichloro-1-fluoropyridinium triflate
3,5-dichloropyridin-2-ol
5-Chloronicotinonitrile
1-(5-chloropyridin-3-yl)piperazine
3-Chloro-5-ethoxypyridine
3,5-DICHLORO-4-NITROPYRIDINE N-OXIDE
4-Bromo-3,5-dichloropyridine
3,5-Dichloro-4-iodopyridine
3,5-dichloro-2-iodopyridine
4-(4-bromophenyl)sulfanylthieno[2,3-c]pyridine-2-carboxamide

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%