Gefitinib impurity 2

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Names

[ CAS No. ]:
246512-44-7

[ Name ]:
Gefitinib impurity 2

[Synonym ]:
2-aMino-4-Methoxy-5-(3-Morpholinopropoxy)benzaMide

Chemical & Physical Properties

[ Molecular Formula ]:
C15H23N3O4

[ Molecular Weight ]:
309.36100

[ Exact Mass ]:
309.16900

[ PSA ]:
101.03000

[ LogP ]:
1.88070

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-amino-4-methoxy-5-(3-morpholinopropoxy)benzonitrile
  • 4-Methoxy-5-(3-Morpholinopropoxy)-2-nitrobenzaMide
  • 4-(3-Chloropropyl)morpholine
  • 3-(3-Morpholinylpropoxy)-4-methoxybenzonitrile
  • Gefitinib impurity 1
  • Isovanillin
  • 3-Hydroxy-4-methoxybenzonitrile

DownStream

  • O-Desmethyl gefitinib
  • Gefitinib
  • Gefitinib impurity 5

Related Compounds

  • Gefitinib Impurity 2
  • Gefitinib impurity 1
  • Gefitinib impurity 5
  • Gefitinib Impurity 35
  • N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)-N-(3-morpholinopropyl)quinazolin-4-amine
  • Thiamine Impurity 2
  • 8-isobutyl-1,6,7-trimethyl-3-(3-methylbenzyl)-1H-imidazo[2,1-f]purine-2,4(3H,8H)-dione
  • 9-(2,3-dimethylphenyl)-1-methyl-3-(3-phenylpropyl)-6,7,8,9-tetrahydropyrimido[2,1-f]purine-2,4(1H,3H)-dione
  • CID 16626133
  • 3-[(4-Fluorophenyl)methyl]-1,6,7-trimethyl-8-(methylpropyl)-1,3,5-trihydro-4-i midazolino[1,2-h]purine-2,4-dione
  • 8-(2-(2-hydroxyethoxy)ethyl)-1,6,7-trimethyl-3-(3-phenylpropyl)-1H-imidazo[2,1-f]purine-2,4(3H,8H)-dione
  • 3-(2,5-dimethylbenzyl)-9-(2,3-dimethylphenyl)-1-methyl-6,7,8,9-tetrahydropyrimido[2,1-f]purine-2,4(1H,3H)-dione
  • 4-(1,6,7-trimethyl-3-(2-methylbenzyl)-2,4-dioxo-3,4-dihydro-1H-imidazo[2,1-f]purin-8(2H)-yl)benzenesulfonamide
  • 1,6,7-trimethyl-3-(2-oxo-2-phenylethyl)-8-(1-phenylethyl)-1H-imidazo[2,1-f]purine-2,4(3H,8H)-dione
  • 3-butyl-9-(2,3-dimethylphenyl)-1-methyl-6,7,8,9-tetrahydropyrimido[2,1-f]purine-2,4(1H,3H)-dione
  • N-(2,4-dimethoxyphenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-2-methylbenzamide
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