Norscopolamine hydrochloride

Names

[ CAS No. ]:
24676-80-0

[ Name ]:
Norscopolamine hydrochloride

[Synonym ]:
norscopolamine,hydrochloride
(S)-3-hydroxy-2-phenyl-propionic acid (1rN,2tH,4tH,5cN)-3-oxa-9-aza-tricyclo[3.3.1.02,4]non-7t-yl ester,hydrochloride
Norscopolamin-hydrochlorid

Chemical & Physical Properties

[ Boiling Point ]:
474.7ºC at 760mmHg

[ Molecular Formula ]:
C16H20ClNO4

[ Molecular Weight ]:
325.78700

[ Flash Point ]:
240.9ºC

[ Exact Mass ]:
325.10800

[ PSA ]:
71.09000

[ LogP ]:
1.70670

[ Vapour Pressure ]:
8.13E-10mmHg at 25°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
RD1575000
CHEMICAL NAME :
1-alpha-H,5-alpha-H-Nortropan-3-alpha-ol, 6-beta,7-beta-epoxy-, (-)-tropate, hydrochloride
CAS REGISTRY NUMBER :
24676-80-0
LAST UPDATED :
199109
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C16-H19-N-O4.Cl-H
MOLECULAR WEIGHT :
325.82

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3020 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 180,155,1969
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
4230 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 180,155,1969
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraduodenal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
860 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 180,155,1969

Synthetic Route

Precursor & DownStream

Precursor

  • Scopolamine hydrobromide

DownStream

  • Oxitropium Bromide

Related Compounds

  • Tyrocidine, hydrochloride
  • Triprolidine hydrochloride
  • Minoxidil hydrochloride
  • Ebaresdax hydrochloride
  • dodecylamine hydrochloride
  • Elacridar hydrochloride
  • 1-Chloro-6,6-difluoro-2-methylheptane
  • 2,2-Difluoro-3-(2-methoxyethoxy)propanoic acid
  • 3-Hydroxy-3-(5-phenylthiophen-2-yl)propanoic acid
  • 3-N,5-N-bis(2-hydroxyethyl)-1H-pyrazole-3,5-dicarboxamide
  • 1-methyl-2-[2-(1H-pyrazol-1-yl)ethyl]piperazine
  • 1-[1-(3-tert-butyl-1-methyl-1H-pyrazol-4-yl)cyclopropyl]ethan-1-amine
  • 1-methyl-5-[(2R)-oxiran-2-yl]-1H-1,2,3-triazole
  • 5-(Thiophen-3-yl)-1-oxa-8-thia-4-azaspiro[5.5]undecane
  • rel-((1R,3S)-3-(((tert-Butyldiphenylsilyl)oxy)methyl)-2,2-dimethylcyclopropyl)methanol
  • (1R)-2-amino-1-(2-methyl-2,3-dihydro-1-benzofuran-5-yl)ethan-1-ol
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