Ethyl 4-Hydroxy-2H-1,2-benzothiazine-3-carboxylate 1,1-Dioxide

Names

[ CAS No. ]:
24683-21-4

[ Name ]:
Ethyl 4-Hydroxy-2H-1,2-benzothiazine-3-carboxylate 1,1-Dioxide

[Synonym ]:
ethyl 4-hydroxy-1,1-dioxo-2H-1λ<sup>6</sup>,2-benzothiazine-3-carboxylate

Chemical & Physical Properties

[ Density]:
1.502g/cm3

[ Boiling Point ]:
452.999ºC at 760 mmHg

[ Melting Point ]:
140 °C

[ Molecular Formula ]:
C11H11NO5S

[ Molecular Weight ]:
269.27400

[ Flash Point ]:
227.766ºC

[ Exact Mass ]:
269.03600

[ PSA ]:
101.08000

[ LogP ]:
2.17780

[ Vapour Pressure ]:
0mmHg at 25°C

[ Index of Refraction ]:
1.623

[ Storage condition ]:
2-8°C

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-((TERT-BUTYLDIMETHYLSILYLOXY)METHYL)-6-((TRIMETHYLSILYL)ETHYNYL)FURO[3,2-B]PYRIDINE
  • Sodium Saccharin
  • methyl 2-(1,1,3-trioxo-1,2-benzothiazol-2-yl)acetate
  • Sodium ethoxide
  • ethyl 2-(N-(2-ethoxy-2-oxoethyl)sulfamoyl)benzoate

DownStream

  • Isoxicam
  • 4-Hydroxy-2-methyl-N-[4-(trifluoromethyl)phenyl]-2H-1,2-benzothia zine-3-carboxamide 1,1-dioxide
  • 4-hydroxy-2-methyl-1,1-dioxo-N-phenyl-1λ6,2-benzothiazine-3-carboxamide
  • N-(4-Chlorophenyl)-4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carb oxamide 1,1-dioxide
  • 4-Hydroxy-2-methyl-N-[3-(trifluoromethyl)phenyl]-2H-1,2-benzothia zine-3-carboxamide 1,1-dioxide
  • Ethyl 4-hydroxy-2-methyl-2H-benzo[e][1,2]thiazine-3-carboxylate 1,1-dioxide
  • 4-hydroxy-2-methyl-1,1-dioxo-1λ6,2-benzothiazine-3-carboxamide
  • 4-methyl-1-naphthalen-1-ylsulfonylpiperidine