SB 328437

[ Molecular Formula ]:
C₂₁H₁₈N₂O₅

[ Molecular Weight ]:
378.37800

[ Exact Mass ]:
378.12200

[ PSA ]:
104.71000

[ LogP ]:
4.36010

Click to get detail MSDS

[ Symbol ]:

GHS07, GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H400

[ Precautionary Statements ]:
P273

[ RIDADR ]:
UN 3077 9 / PGIII

CCR3 antagonists: a survey of the patent literature.

Expert Opin. Ther. Pat. 19(8) , 1109-32, (2009)

Since the mid-1990s, there has been significant effort invested in the discovery and clinical development of CC chemokine receptor-3 (CCR3) antagonists as potential therapeutics for airway disease.A p...

Selective suppression of Th2-mediated airway eosinophil infiltration by low-molecular weight CCR3 antagonists.

Int. Immunol. 19(8) , 913-21, (2007)

The effects of selective CC chemokine receptor (CCR)-3 antagonists on antigen-induced leukocyte accumulation in the lungs of mice adoptively transferred with in vitro-differentiated T(h)1 and T(h)2 we...

CCR3 and choroidal neovascularization.

PLoS ONE 6 , e17106, (2011)

Age-related macular degeneration (AMD) is the leading cause of irreversible blindness in the elderly in industrialized countries. The "wet" AMD, characterized by the development of choroidal neovacula...

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