Phorbol 12,13-diacetate

[ Density]:
1.34g/cm3

[ Boiling Point ]:
585.7ºC at 760 mmHg

[ Molecular Formula ]:
C₂₄H₃₂O₈

[ Molecular Weight ]:
448.50600

[ Flash Point ]:
195.4ºC

[ Exact Mass ]:
448.21000

[ PSA ]:
130.36000

[ LogP ]:
1.07170

[ Vapour Pressure ]:
3.69E-16mmHg at 25°C

[ Index of Refraction ]:
1.592

Click to get detail MSDS

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H300 + H310 + H330-H315-H319-H335

[ Precautionary Statements ]:
P260-P264-P280-P284-P301 + P310-P302 + P350

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ Hazard Codes ]:
T+: Very toxic;

[ Risk Phrases ]:
26/27/28-36/37/38

[ Safety Phrases ]:
26-27-36/37/39-45

[ RIDADR ]:
UN 2811 6.1/PG 3

[ WGK Germany ]:
3

[ RTECS ]:
GZ0651000

[ Packaging Group ]:
II

[ Hazard Class ]:
6.1(a)

Click to get detail synthetic route

Precursor

DownStream

Light-dependent translocation of arrestin in rod photoreceptors is signaled through a phospholipase C cascade and requires ATP.

Cell. Signal. 22(3) , 447-56, (2010)

Partitioning of cellular components is a critical mechanism by which cells can regulate their activity. In rod photoreceptors, light induces a large-scale translocation of arrestin from the inner segm...

VNN1, a potential biomarker for pancreatic cancer-associated new-onset diabetes, aggravates paraneoplastic islet dysfunction by increasing oxidative stress.

Cancer Lett. 373 , 241-50, (2016)

In our previous clinical microarray analysis, we were the first to report on Vanin-1 (VNN1) as a novel clinically derived biomarker of pancreatic cancer-associated new-onset diabetes (PCAND). The func...

An improved model of predicting hepatocarcinogenic potential in rats by using gene expression data.

J. Appl. Toxicol. 36 , 296-308, (2016)

Carcinogenicity studies using animals are expensive and time consuming. Therefore, the development of a highly accurate carcinogenicity prediction system to interpret short-term test results would be ...

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