Amino methacrylate copolymer

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Names

[ CAS No. ]:
24938-16-7

[ Name ]:
Amino methacrylate copolymer

[Synonym ]:
Basic butylated methacrylate copolyme

Chemical & Physical Properties

[ Boiling Point ]:
187ºC at 760mmHg

[ Molecular Formula ]:
C21H37NO6

[ Molecular Weight ]:
399.522

[ Flash Point ]:
>250℃

[ Exact Mass ]:
399.262085

[ PSA ]:
82.14000

[ LogP ]:
3.30860

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
OZ3688000
CHEMICAL NAME :
Methacrylic acid, butyl ester, polymer with 2-(dimethylamino)ethyl methacrylate and methyl methacrylate
CAS REGISTRY NUMBER :
24938-16-7
LAST UPDATED :
199701
DATA ITEMS CITED :
2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TEST SYSTEM :
Rodent - mouse
DOSE/DURATION :
800 mg/kg
REFERENCE :
APHGAO Acta Pharmaceutica Hungarica. (Kultura, POB 149, H-1389 Budapest, Hungary) 1953- Adopts V.24 in 1955. Volume(issue)/page/year: 56,97,1986

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Articles

Improved supersaturation and oral absorption of dutasteride by amorphous solid dispersions.

Chem. Pharm. Bull. 60(11) , 1468-73, (2012)

In this study, amorphous solid dispersions containing dutasteride and various excipients, manufactured by spray-drying processes, were characterized to determine the effects on their ability to form s...

Effect of aminoalkyl methacrylate copolymer E/HCl on in vivo absorption of poorly water-soluble drug.

Drug Dev. Ind. Pharm. 39(11) , 1698-705, (2013)

This study aimed to investigate in vivo absorption of tacrolimus formulated as a solid dispersion using Eudragit E®/HCl (E-SD). E-SD is an aminoalkyl methacrylate copolymer that can be dissolved under...

Eudragit E as excipient for production of granules and tablets from Phyllanthus niruri L spray-dried extract.

AAPS PharmSciTech 8(2) , Article 34, (2007)

The aim of this study was to investigate the feasibility of using Eudragit E as a granulating agent for a spray-dried extract from Phyllanthus niruri to obtain tablets containing a high dose of this p...


More Articles


Related Compounds

  • 3-[cyclohexyl({[(9H-fluoren-9-yl)methoxy]carbonyl})amino]-2,2-dimethylpropanoic acid
  • 3-{[(Tert-butoxy)carbonyl](cyclohexyl)amino}-2,2-dimethylpropanoic acid
  • rac-methyl (1R,2S)-2-[(piperidin-2-yl)methyl]cyclopropane-1-carboxylate
  • 5-bromo-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-nitropyridine-4-carboxylic acid
  • 2-{[(Benzyloxy)carbonyl]amino}-5-bromo-3-nitropyridine-4-carboxylic acid
  • 7-{[(9H-fluoren-9-yl)methoxy]carbonyl}-1,1-dioxo-1lambda6-thia-7-azaspiro[3.5]nonane-2-carboxylic acid
  • Tert-butyl 1,4-dioxa-8-azaspiro[4.5]decane-6-carboxylate
  • 2,3-difluoro-N,N-dimethyl-6-(pyrrolidin-3-yl)aniline
  • 6-Bromo-2-(bromomethyl)pyrazolo[1,5-a]pyrimidine
  • rac-(1R,2S)-2-(4-methyl-3,4-dihydro-2H-1,4-benzoxazin-6-yl)cyclopropan-1-amine
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