Amino methacrylate copolymer

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Names

[ CAS No. ]:
24938-16-7

[ Name ]:
Amino methacrylate copolymer

[Synonym ]:
Basic butylated methacrylate copolyme

Chemical & Physical Properties

[ Boiling Point ]:
187ºC at 760mmHg

[ Molecular Formula ]:
C₂₁H₃₇NO₆

[ Molecular Weight ]:
399.522

[ Flash Point ]:
>250℃

[ Exact Mass ]:
399.262085

[ PSA ]:
82.14000

[ LogP ]:
3.30860

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: OZ3688000

CHEMICAL NAME :: Methacrylic acid, butyl ester, polymer with 2-(dimethylamino)ethyl methacrylate and methyl methacrylate

CAS REGISTRY NUMBER :: 24938-16-7

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TEST SYSTEM :: Rodent - mouse

DOSE/DURATION :: 800 mg/kg

REFERENCE :: APHGAO Acta Pharmaceutica Hungarica. (Kultura, POB 149, H-1389 Budapest, Hungary) 1953- Adopts V.24 in 1955. Volume(issue)/page/year: 56,97,1986

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Articles

Improved supersaturation and oral absorption of dutasteride by amorphous solid dispersions.

Chem. Pharm. Bull. 60(11) , 1468-73, (2012)

In this study, amorphous solid dispersions containing dutasteride and various excipients, manufactured by spray-drying processes, were characterized to determine the effects on their ability to form s...

Effect of aminoalkyl methacrylate copolymer E/HCl on in vivo absorption of poorly water-soluble drug.

Drug Dev. Ind. Pharm. 39(11) , 1698-705, (2013)

This study aimed to investigate in vivo absorption of tacrolimus formulated as a solid dispersion using Eudragit E®/HCl (E-SD). E-SD is an aminoalkyl methacrylate copolymer that can be dissolved under...

Eudragit E as excipient for production of granules and tablets from Phyllanthus niruri L spray-dried extract.

AAPS PharmSciTech 8(2) , Article 34, (2007)

The aim of this study was to investigate the feasibility of using Eudragit E as a granulating agent for a spray-dried extract from Phyllanthus niruri to obtain tablets containing a high dose of this p...

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