Urea,N-[2-(3,4-dimethoxyphenyl)ethyl]-

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Names

[ CAS No. ]:
25017-47-4

[ Name ]:
Urea,N-[2-(3,4-dimethoxyphenyl)ethyl]-

[Synonym ]:
1-(3,4-dimethoxyphenethyl)urea
N-(3,4-dimethoxyphenethyl)urea
(3,4-Dimethoxy-phenaethyl)-harnstoff
1-2-(3,4-dimethoxyphenyl)ethyl urea
N-<2-(3,4-dimethoxyphenylethyl)>urea
Urea,(3,4-dimethoxyphenethyl)
(3,4-dimethoxy-phenethyl)-urea

Chemical & Physical Properties

[ Density]:
1.141g/cm3

[ Boiling Point ]:
367.6ºC at 760 mmHg

[ Molecular Formula ]:
C11H16N2O3

[ Molecular Weight ]:
224.25600

[ Flash Point ]:
176.1ºC

[ Exact Mass ]:
224.11600

[ PSA ]:
73.58000

[ LogP ]:
2.00580

[ Vapour Pressure ]:
1.35E-05mmHg at 25°C

[ Index of Refraction ]:
1.533

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YS9863000
CHEMICAL NAME :
Urea, (3,4-dimethoxyphenethyl)-
CAS REGISTRY NUMBER :
25017-47-4
BEILSTEIN REFERENCE NO. :
2736376
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C11-H16-N2-O3
MOLECULAR WEIGHT :
224.29
WISWESSER LINE NOTATION :
ZVM2R CO1 DO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>3 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949- Volume(issue)/page/year: 21,366,1969
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
336 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 52,211,1934

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 3,4-Dimethoxyphenethylamine
  • Methyl carbamate
  • Potassium cyanate
  • 3,4-Dimethoxyphenethylamine (hydrochloride)
  • Urea
  • 3,4-Dimethoxyphenethyl isocyanate
  • 3,4-dimethoxyphenylpropionic acid chloride
  • 3-(3,4-Dimethoxyphenyl)propionic acid

DownStream

  • 4H-Pyrimido(6,1-a)isoquinolin-4-one, 6,7-dihydro-9,10-dimethoxy-2-(eth yl(2,4,6-trimethylphenyl)amino)-, hydrate (2:1)
  • N-(9,10-dimethoxy-4-oxo-6,7-dihydropyrimido[6,1-a]isoquinolin-2-yl)-N-(2,4,6-trimethylphenyl)acetamide
  • 9,10-dimethoxy-3-propan-2-yl-2-(2,4,6-trimethylphenyl)imino-6,7-dihydropyrimido[6,1-a]isoquinolin-4-one

Related Compounds

  • (E)-N-[2-(3,4-dimethoxyphenyl)ethyl]-N-methyl-3-pyridin-3-ylprop-2-enamide
  • (E)-N-[2-(3,4-dimethoxyphenyl)ethyl]-2-methyl-3-(4-nitrophenyl)prop-2-enamide
  • ethyl N-[2-(3,4-dimethoxyphenyl)ethyl]carbamodithioate
  • Benzeneacetamide,N-[2-(3,4-dimethoxyphenyl)ethyl]-a-phenyl-
  • ethyl N-[2-(3,4-dimethoxyphenyl)ethyl]carbamate
  • McN5691
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • N-methyl-1-(propan-2-yl)-1H-imidazol-4-amine
  • 3-(benzo[d][1,3]dioxole-5-carbonyl)-8-methoxy-2H-chromen-2-one
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine