5-hydroxyindomethacin

Suppliers

Names

[ CAS No. ]:
2504-32-7

[ Name ]:
5-hydroxyindomethacin

[Synonym ]:
2-[1-(4-chlorobenzoyl)-5-hydroxy-2-methylindol-3-yl]acetic acid

Chemical & Physical Properties

[ Density]:
1.4g/cm3

[ Boiling Point ]:
518.8ºC at 760mmHg

[ Melting Point ]:
217-219ºC

[ Molecular Formula ]:
C18H14ClNO4

[ Molecular Weight ]:
343.76100

[ Flash Point ]:
267.6ºC

[ Exact Mass ]:
343.06100

[ PSA ]:
79.53000

[ LogP ]:
3.62430

[ Vapour Pressure ]:
1.37E-11mmHg at 25°C

[ Index of Refraction ]:
1.651

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Indometacin
  • tert-butyl 2-(1-(4-chlorobenzoyl)-5-hydroxy-2-methyl-1H-indol-3-yl)acetate
  • tert-butyl 4-oxopentanoate
  • 4-Benzyloxyphenylhydrazine hydrochloride
  • t-butyl 5-benzyloxy-2-methyl indole acetate

DownStream

Related Compounds

  • 5-[(4-phenylphenyl)methylidene]imidazolidine-2,4-dione
  • 5-(3-formyl-2-hydroxyphenyl)benzene-1,3-dicarboxylic acid
  • 5,8-difluoro-4-methyl-1,2,3,4-tetrahydronaphthalen-1-ol
  • 5-(p-Toluenesulfonate)-2,3-O-isopropylidene-2-C-methyl-D-ribonic-gamma-lactone
  • 5-(oxiran-2-ylmethoxy)-2,3,4,9-tetrahydro-1H-carbazole
  • 5-(2,4-difluorophenyl)-2-hydroxy-3-sulfooxybenzoic acid
  • 2-[3-(4,4-Difluoropiperidine-1-carbonyl)piperidin-1-yl]-4,7-dimethoxy-1,3-benzothiazole
  • 4,4-difluoro-1-{1-[2-(2H-1,2,3-triazol-2-yl)ethyl]piperidine-3-carbonyl}piperidine
  • 4,4-difluoro-1-{1-[2-(1H-1,2,3-triazol-1-yl)ethyl]piperidine-3-carbonyl}piperidine
  • Propanamide, 2-amino-N-[2-(5-methyl-1,3,4-thiadiazol-2-yl)ethyl]-, (2S)-
  • 4,8,8,10,10-Pentamethyl-1-oxa-5,9-diazaspiro[5.5]undecane
  • 4-(Methoxymethyl)-9-(2-methylpropyl)-1-oxa-5,9-diazaspiro[5.5]undecane
  • 2,2,9,9-Tetramethyl-1-oxa-5-azaspiro[5.6]dodecane
  • 2-[4-ethyl-1-(propan-2-yl)-1H-pyrazol-3-yl]ethan-1-ol
  • (2E)-2-[(pyrimidin-4-yl)methylidene]butanoic acid
  • 1-(Bromomethyl)-1-(2,2-difluoropropyl)-3-methylcyclobutane
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.