Acetamide,N-(7-fluoro-9H-fluoren-2-yl)-N-hydroxy-

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Names

[ CAS No. ]:
2508-18-1

[ Name ]:
Acetamide,N-(7-fluoro-9H-fluoren-2-yl)-N-hydroxy-

[Synonym ]:
7-Fluoro-2-faa
7-fluoro-N-hydroxy-2-acetamidofluorene
N-Hydroxy-7-fluoro-2-acetylaminofluorene
7-Fluoro-n-hydroxy-n-2-acetylaminofluorene
Acetamide,N-7-fluorofluoren-2-yl-N-hydroxy

Chemical & Physical Properties

[ Density]:
1.389g/cm3

[ Boiling Point ]:
458.4ºC at 760mmHg

[ Molecular Formula ]:
C15H12FNO2

[ Molecular Weight ]:
257.26000

[ Flash Point ]:
231ºC

[ Exact Mass ]:
257.08500

[ PSA ]:
40.54000

[ LogP ]:
3.13900

[ Vapour Pressure ]:
3.39E-09mmHg at 25°C

[ Index of Refraction ]:
1.676

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AL0525000
CHEMICAL NAME :
Acetohydroxamic acid, N-(7-fluorofluoren-2-yl)-
CAS REGISTRY NUMBER :
2508-18-1
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C15-H12-F-N-O2
MOLECULAR WEIGHT :
257.28
WISWESSER LINE NOTATION :
L B656 HHJ ENQV1 KF

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
675 mg/kg/10W-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Gastrointestinal - tumors Liver - tumors

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
15 nmol/plate
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 67,85,1979

Safety Information

[ HS Code ]:
2924299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 9H-Fluorene,2-fluoro-7-nitro-
  • Acetyl chloride

DownStream

  • Acetamide,N-[7-fluoro-3-(methylthio)-9H-fluoren-2-yl]-
  • 9H-Fluoren-2-amine,7-fluoro-3-(methylthio)-
  • N-(7-fluoro-1-methylsulfanyl-9H-fluoren-2-yl)acetamide
  • [acetyl-(7-fluoro-9H-fluoren-2-yl)amino] acetate

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Related Compounds

  • Acetamide,N-(7-fluoro-9H-fluoren-2-yl)-
  • Acetamide, N-(7-acetyl-9H-fluoren-2-yl)-N-hydroxy-
  • Acetamide,N-(7-fluoro-3-nitro-9H-fluoren-2-yl)-
  • Acetamide,N-[7-fluoro-3-(methylthio)-9H-fluoren-2-yl]-
  • Acetamide,N-[7-fluoro-3-(methylthio)-9-oxo-9H-fluoren-2-yl]-
  • Acetamide,N-(7-fluoro-3-nitro-9-oxo-9H-fluoren-2-yl)-
  • (4-(3-Chlorophenyl)piperazin-1-yl)(4-(3-methoxypyrrolidin-1-yl)phenyl)methanone
  • 4-(4-methoxypiperidin-1-yl)-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzamide
  • N-(3,5-dimethylphenyl)-4-(4-methoxypiperidin-1-yl)benzamide
  • N-(benzo[d]thiazol-2-yl)-4-(4-methoxypiperidin-1-yl)benzamide
  • (4-(4-Methoxypiperidin-1-yl)phenyl)(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)methanone
  • N-(2-amino-2-oxoethyl)-4-(4-methoxypiperidin-1-yl)benzamide
  • 4-(4-methoxypiperidin-1-yl)-N-(3-(methylthio)phenyl)benzamide
  • N-(3-chloro-4-fluorophenyl)-4-(4-methoxypiperidin-1-yl)benzamide
  • N-(2,4-difluorophenyl)-4-(4-methoxypiperidin-1-yl)benzamide
  • 4-(4-methoxypiperidin-1-yl)-N-(pyridin-2-ylmethyl)benzamide
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