O,S-DIETHYL METHYLPHOSPHONOTHIOATE

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Names

[ CAS No. ]:
2511-10-6

[ Name ]:
O,S-DIETHYL METHYLPHOSPHONOTHIOATE

[Synonym ]:
O,S-Diethyl methylthiophosphonate
methyl-thiophosphonic acid O,S-diethyl ester
OSDMP
Phosphonothioic acid,methyl-,O,S-diethyl ester
O-Ethyl-S-ethylmethylphosphonothiolate
Methylphosphonothioic acid O,S-diethyl ester
MFCD01705977
O,S-Diethyl methyl phosphonothioate
O,S-diethyl methylphosphonate
O,S-diethyl methylphosphonothionate
LG 61

Chemical & Physical Properties

[ Density]:
1.081g/cm3

[ Boiling Point ]:
208ºC at 760mmHg

[ Molecular Formula ]:
C5H13O2PS

[ Molecular Weight ]:
168.19400

[ Flash Point ]:
79.6ºC

[ Exact Mass ]:
168.03700

[ PSA ]:
61.41000

[ LogP ]:
2.59890

[ Vapour Pressure ]:
0.315mmHg at 25°C

[ Index of Refraction ]:
1.45

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TB1085000
CHEMICAL NAME :
Phosphonothioic acid, methyl-, O,S-diethyl ester
CAS REGISTRY NUMBER :
2511-10-6
BEILSTEIN REFERENCE NO. :
1753418
LAST UPDATED :
199706
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C5-H13-O2-P-S
MOLECULAR WEIGHT :
168.21

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
6 mg/kg
TOXIC EFFECTS :
Behavioral - tetany Lungs, Thorax, or Respiration - dyspnea Kidney, Ureter, Bladder - urine volume increased
REFERENCE :
JAFCAU Journal of Agricultural and Food Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1953- Volume(issue)/page/year: 32,774,1984
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IAEC** Interagency Collaborative Group on Environmental Carcinogenesis, National Cancer Institute, Memorandum, June 17, 1974 Volume(issue)/page/year: 17JUN1974
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
5620 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IAEC** Interagency Collaborative Group on Environmental Carcinogenesis, National Cancer Institute, Memorandum, June 17, 1974 Volume(issue)/page/year: 17JUN1974
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
>24 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IAEC** Interagency Collaborative Group on Environmental Carcinogenesis, National Cancer Institute, Memorandum, June 17, 1974 Volume(issue)/page/year: 17JUN1974
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
2480 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IAEC** Interagency Collaborative Group on Environmental Carcinogenesis, National Cancer Institute, Memorandum, June 17, 1974 Volume(issue)/page/year: 17JUN1974

Safety Information

[ RIDADR ]:
UN3278

[ Packaging Group ]:
II

[ Hazard Class ]:
6.1

Synthetic Route

Precursor & DownStream

Precursor

  • Na salt of O-ethylmethylthiophosphonic acid
  • Ethyl iodide
  • 1-[chloro(methyl)phosphoryl]oxyethane
  • Ethanethiol
  • o,o'-diethyl methylphosphonothioate
  • Diethyl disulfide
  • ETHYL METHYLPHOSPHINATE
  • o-ethyl methylphosphonothioate
  • 1,1-diethoxyprop-1-ene
  • Bromoethane

DownStream

  • Ethanethiol
  • Diethyl disulfide
  • methyl-methanesulfonate
  • O-ethyl methylphosphonate
  • Ethyl dichlorophosphate

Related Compounds

  • O,S-DIETHYL METHYLPHOSPHONOTHIOATE
  • O,S-diethyl-dithiophosphoric acid
  • O,S-Diethyl dithiocarbonate
  • O-cyclohexyl O,S-diethyl thiophosphate
  • thiosulfurous acid O,S-diethyl ester
  • thiooxalic acid O,S-diethyl ester
  • N-(furan-3-ylmethyl)-N-(2-methoxyethyl)-2-(methylthio)nicotinamide
  • 2-(2-fluorophenoxy)-N-(furan-3-ylmethyl)-N-(2-methoxyethyl)acetamide
  • 2-(2-chlorophenyl)-N-(furan-3-ylmethyl)-N-(2-methoxyethyl)acetamide
  • N-(furan-3-ylmethyl)-N-(2-methoxyethyl)-1-naphthamide
  • 2-chloro-6-fluoro-N-(furan-3-ylmethyl)-N-(2-methoxyethyl)benzamide
  • 3-Methyl-1-[3-(methylamino)propyl]-1,2-dihydroquinoxalin-2-one hydrochloride
  • 1-Tert-butoxy-2-cyclopropoxy-3-isopropylbenzene
  • (E)-methyl (4-(N-((1-(3-(furan-2-yl)acryloyl)piperidin-4-yl)methyl)sulfamoyl)phenyl)carbamate
  • N-(furan-3-ylmethyl)-N-(2-methoxyethyl)-2-methylimidazo[1,2-a]pyridine-3-carboxamide
  • N-(furan-3-ylmethyl)-N-(2-methoxyethyl)-3-(phenylthio)propanamide