Clobetasol

Suppliers

Names

[ Name ]:
Clobetasol

[Synonym ]:
(8S,9R,10S,11S,13S,14S,16S,17R)-17-(2-chloroacetyl)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
UNII-ADN79D536H
Clobetasolum
EINECS 246-633-8
Clobetasol [INN:BAN]
21-Chloro-9-fluoro-11beta,17-dihydroxy-16beta-methylpregna-1,4-diene-3,20-dione
Clobetasolum [INN-Latin]

Chemical & Physical Properties

[ Density]:
1.32 g/cm3

[ Boiling Point ]:
555.1ºC at 760 mmHg

[ Melting Point ]:
195 - 197C (decomposes)ºC

[ Molecular Formula ]:
C₂₂H₂₈ClFO₄

[ Molecular Weight ]:
410.90700

[ Flash Point ]:
289.5ºC

[ Exact Mass ]:
410.16600

[ PSA ]:
74.60000

[ LogP ]:
3.14220

[ Vapour Pressure ]:
1.23E-14mmHg at 25°C

[ Index of Refraction ]:
1.582

[ Storage condition ]:
-20?C Freezer

Safety Information

[ Symbol ]:

GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H360Df-H373-H413

[ Precautionary Statements ]:
P201-P308 + P313

[ Target Organs ]:
Adrenal gland, Immune system

[ Hazard Codes ]:
T

[ Risk Phrases ]:
61-48/20/21-53-62

[ Safety Phrases ]:
53-36/37-45

[ RIDADR ]:
NONH for all modes of transport

Articles

Topical steroids for chronic wounds displaying abnormal inflammation.

Ann. R. Coll. Surg. Engl. 95(4) , 291-6, (2013)

Chronic, non-healing wounds are often characterised by an excessive, and detrimental, inflammatory response. We review our experience of using a combined topical steroid, antibiotic and antifungal pre...

Impact of clobetasol propionate 0.05% spray on health-related quality of life in patients with plaque psoriasis.

Journal. of. Drugs in. Dermatology. 11(11) , 1348-54, (2012)

Psoriasis causes significant distress and impairment in health-related quality of life (QOL) in afflicted patients. For this reason, QOL is an essential and important measure of treatment outcome in p...

Clobetasol propionate spray 0.05% for the treatment of moderate to severe plaque psoriasis.

Cutis. 89(2) , 89-94, (2012)

Clobetasol propionate is a super-high potent class 1 topical corticosteroid available in several formulations, including a spray formulation that is approved for use up to 4 weeks in patients aged 18 ...

Clobetasolpropionate
Clobetasol Propionate-d5
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