3,3,3-Trifluoropropanoic acid

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Names

[ CAS No. ]:
2516-99-6

[ Name ]:
3,3,3-Trifluoropropanoic acid

[Synonym ]:
PROPANOIC ACID,3,3,3-TRIFLUORO
Propanoic acid, 3,3,3-trifluoro-
C3H3F3O2
TFPA
3,3,3-trifluoromethylpropionic acid
trifluoromethylacetic acid
2-trifluoromethylacetic acid
MFCD00153292
3,3,3-Trifluoropropanoic acid
3,3,3-trifluoroacetic acid
3,3,3-Trifluoropropionic acid
3,3,3-trifluoro-propionic acid
3,3,3-TRIFLUORO PROPANOIC ACID

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
128.0±35.0 °C at 760 mmHg

[ Melting Point ]:
9.7 °C(lit.)

[ Molecular Formula ]:
C3H3F3O2

[ Molecular Weight ]:
128.050

[ Flash Point ]:
31.2±25.9 °C

[ Exact Mass ]:
128.008514

[ PSA ]:
37.30000

[ LogP ]:
1.02

[ Vapour Pressure ]:
6.6±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.326

MSDS

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
C:Corrosive;

[ Risk Phrases ]:
R34

[ Safety Phrases ]:
S26-S36/37/39-S45

[ RIDADR ]:
UN 3265 8/PG 2

[ WGK Germany ]:
3

[ Packaging Group ]:
II

[ Hazard Class ]:
8

[ HS Code ]:
2915900090

Precursor & DownStream

Precursor

  • 3,3,3-Trifluoropropanal
  • 3,3,3-TRIFLUOROPROPIONYLCHLORIDE
  • 3,3,3-trifluoro-2-chloropropionyl chloride
  • 2-(2,2,2-trifluoroethylidene)-1,3-dithiane
  • 1-Chloro-1,1,3,3,3-pentafluoropropane
  • 1,1-Dichloro-1,3,3,3-tetrafluoropropane
  • Methyl 3,3,3-trifluoropropionate
  • 3,3,3-Trifluoropropanol
  • 3,3,3-Trifluoropropanal dimethylacetal
  • 2-(trifluoromethyl)malononitrile

DownStream

  • 3,3,3-TRIFLUOROPROPIONYLCHLORIDE
  • 1,1,1-Trifluoroethane
  • Carbon dioxide
  • Ethyl 3,3,3-trifluoropropanoate
  • Methyl 3,3,3-trifluoropropionate
  • 5,6-Dichloro-2-(2,2,2-trifluoroethyl)-1H-benzimidazole

Customs

[ HS Code ]: 2915900090

[ Summary ]:
2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0%

Articles

The many roles for fluorine in medicinal chemistry.

J. Med. Chem. 51 , 4359-69, (2008)

Accessibility of N-acyl-D-mannosamines to N-acetyl-D-neuraminic acid aldolase.

Carbohydr. Res. 339(12) , 2091-100, (2004)

N-Acetyl-D-neuraminic acid (NeuNAc) aldolase is an important enzyme for the metabolic engineering of cell-surface NeuNAc using chemically modified D-mannosamines. To explore the optimal substrates for...

Synthesis of ethyl 3,3,3-trifluoropropionate from 2-bromo-3,3,3-trifluoropropene. Inoue M, et al.

J. Fluor. Chem. 167 , 135-138, (2014)


More Articles


Related Compounds

  • 2-Amino-3,3,3-trifluoropropanoic acid
  • 2-bromo-3,3,3-trifluoropropanoic acid
  • 2-chloro-3,3,3-trifluoropropanoic acid
  • 2-hydroxy-3,3,3-trifluoropropanoic acid
  • 2-hydroxy-3,3,3-trifluoropropanoic acid
  • 2,2-diallyl-3,3,3-trifluoropropanoic acid