2,4-D isooctyl ester
Suppliers
Names
[ CAS No. ]:
25168-26-7
[ Name ]:
2,4-D isooctyl ester
[Synonym ]:
6-Methylheptyl (2,4-dichlorophenoxy)acetate
Esteron GE
Silvapron D
Acetic acid,(2,4-dichlorophenoxy)-,isooctyl ester
Agro-D-Ester
EINECS 246-704-3
2,4-D isooctyl ester
Agroxone 5
2,4,6-TRIS-(TRIFLUOROMETHYL)BENZIMIDAZOLE
Weedtrine-II
MFCD00137356
Herbate Ester 80
Chemical & Physical Properties
[ Density]:
1.15 g/cm3
[ Boiling Point ]:
396.9ºC at 760 mmHg
[ Melting Point ]:
12ºC
[ Molecular Formula ]:
C16H22Cl2O3
[ Molecular Weight ]:
333.25000
[ Flash Point ]:
48ºC
[ Exact Mass ]:
332.09500
[ PSA ]:
35.53000
[ LogP ]:
5.13180
[ Vapour Pressure ]:
1.65E-06mmHg at 25°C
[ Index of Refraction ]:
1.506
[ Water Solubility ]:
<0.1 g/100 mL at 21 ºC
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AG8575000
- CHEMICAL NAME :
- Acetic acid, (2,4-dichlorophenoxy)-, isooctyl ester
- CAS REGISTRY NUMBER :
- 25168-26-7
- LAST UPDATED :
- 199603
- DATA ITEMS CITED :
- 15
- MOLECULAR FORMULA :
- C16-H22-Cl2-O3
- MOLECULAR WEIGHT :
- 333.28
- WISWESSER LINE NOTATION :
- GR CG DO1VO5Y1&1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 982 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- >2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 14 gm/kg/78W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - tumors Liver - tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 21 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Blood - tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 1370 mg/kg
- SEX/DURATION :
- female 6-15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Newborn - live birth index (measured after birth)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 302 mg/kg
- SEX/DURATION :
- female 9-12 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - musculoskeletal system
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 188 mg/kg
- SEX/DURATION :
- female 6-15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - homeostasis Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 1131 mg/kg
- SEX/DURATION :
- female 6-15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 528 mg/kg
- SEX/DURATION :
- female 8-11 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 1680 mg/kg
- SEX/DURATION :
- female 7-15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 438 mg/kg
- SEX/DURATION :
- female 8-12 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 1170 mg/kg
- SEX/DURATION :
- female 6-14 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - extra-embryonic structures (e.g., placenta, umbilical cord) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - eye/ear
MUTATION DATA
- TYPE OF TEST :
- Sister chromatid exchange
- TEST SYSTEM :
- Human Lymphocyte
- DOSE/DURATION :
- 50 ug/L
- REFERENCE :
- DBABEF Doga Bilim Dergisi, Seri A2: Biyoloji. Natural Science Journal, Series A2. (Turkiye Bilimsel ve Teknik Arastirma Kurumu, Ataturk Bul. No. 221, Kavaklidere, Ankara, Turkey) V.8- 1984- Volume(issue)/page/year: 8,105,1984 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 15,111,1977 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 82947 No. of Facilities: 100 (estimated) No. of Industries: 4 No. of Occupations: 5 No. of Employees: 291 (estimated)
Safety Information
[ Hazard Codes ]:
T:Toxic;
[ Risk Phrases ]:
R25;R36/38;R40
[ Safety Phrases ]:
S26-S36/37-S45
[ RIDADR ]:
UN 2810
[ RTECS ]:
AG8575000
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1(b)