AZD-7547

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Names

[ CAS No. ]:
252017-04-2

[ Name ]:
AZD-7547

[Synonym ]:
4-[(3-Chloro-4-{[(2R)-3,3,3-trifluoro-2-hydroxy-2-methylpropanoyl]amino}phenyl)sulfonyl]-N,N-dimethylbenzamide
(R)-N-[2-Chloro-4-(4-mesylphenylsulphinyl)phenyl]-2-hydroxy-2-methyl-3,3,3-trifluoropropanamide
(4R)-3-[(2E)-1-Oxo-2-penten-1-yl]-4-phenyl-2-oxazolidinone
(4R)-3-[(2E)-1-Oxo-2-pentenyl]-4-phenyl-2-oxazolidinone
(R)-N-{2-Chloro-4-[4-(N,N-dimethylcarbamoyl)phenylsulphonyl]phenyl}-2-hydroxy-2-methyl-3,3,3-trifluoropropanamide
(R)-N-[(E)-EtCHCHC(O)]-4-phenyl-1,3-oxazolidin-2-one
Benzamide, 4-[[3-chloro-4-[[(2R)-3,3,3-trifluoro-2-hydroxy-2-methyl-1-oxopropyl]amino]phenyl]sulfonyl]-N,N-dimethyl-
AZD-7547
AZD7545

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
683.1±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C19H18ClF3N2O5S

[ Molecular Weight ]:
478.870

[ Flash Point ]:
366.9±31.5 °C

[ Exact Mass ]:
478.057709

[ PSA ]:
67.25000

[ LogP ]:
2.66

[ Vapour Pressure ]:
0.0±2.2 mmHg at 25°C

[ Index of Refraction ]:
1.573

[ Storage condition ]:
-20℃

Safety Information

[ Hazard Codes ]:
Xi

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Oxalyl chloride
  • 2-Chloroaniline
  • 2-chloro-4-mercaptoaniline
  • 2-chloro-4-thiocyanato-aniline
  • 4-((4-amino-3-chlorophenyl)thio)-N,N-dimethylbenzamide
  • 4-((4-amino-3-chlorophenyl)thio)benzonitrile
  • 4-Bromobenzoyl chloride
  • 4-Bromobenzoic acid

DownStream

Related Compounds

  • AZD 3147
  • AZD 1678
  • AZD-8165
  • AZD 1283
  • AZD-5153
  • AZD-6244
  • 2-[({5-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1,2-oxazol-3-yl}formamido)methyl]-2-methylbutanoic acid
  • (2S)-2-({5-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1,2-oxazol-3-yl}formamido)-4-(methylsulfanyl)butanoic acid
  • (2R)-2-({5-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1,2-oxazol-3-yl}formamido)-4-(methylsulfanyl)butanoic acid
  • (9H-fluoren-9-yl)methyl (2S)-2-{2-[(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)oxy]-2-oxoethyl}pyrrolidine-1-carboxylate
  • 4-({5-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1,2-oxazol-3-yl}formamido)hexanoic acid
  • rac-(1R,3S)-3-{5-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1,2-oxazole-3-amido}cyclopentane-1-carboxylic acid
  • 2-{5-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1,2-oxazole-3-carbonyl}-2-azabicyclo[2.1.1]hexane-1-carboxylic acid
  • 3-{5-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1,2-oxazole-3-carbonyl}-3-azabicyclo[3.1.0]hexane-1-carboxylic acid
  • (2S)-2-[(2R,3S)-3-(benzyloxy)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]-4-hydroxybutanoic acid
  • (2R)-2-[(2R,3S)-3-(benzyloxy)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]-4-hydroxybutanoic acid
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