4-Morpholinoaniline

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Names

[ Name ]:
4-Morpholinoaniline

[Synonym ]:
benzenamine, 4-(4-morpholinyl)-
4-Morpholinyl aniline
4-Morpholin-4-yl-phenylamine
4-(4-Morpholinyl)aniline
4-(4-Aminophenyl)morpholine
EINECS 219-760-1
Morpholine, 4-(p-aminophenyl)-
4-(morpholin-4-yl)aniline
4-Morpholinoaniline
Benzenamine, 4- (4-morpholinyl)-
4-(Morpholin-4-yl)anilin
p-Morpholinoaniline
4-morpholinobenzenamine
MFCD00006169

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
368.0±37.0 °C at 760 mmHg

[ Melting Point ]:
132-135 °C(lit.)

[ Molecular Formula ]:
C₁₀H₁₄N₂O

[ Molecular Weight ]:
178.23

[ Flash Point ]:
176.4±26.5 °C

[ Exact Mass ]:
178.110611

[ PSA ]:
38.49000

[ LogP ]:
0.08

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.590

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R20/21/22

[ Safety Phrases ]:
S26-S37/39-S36/37/39-S22

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2934999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

4-(4-nitrophenyl)morpholine
4-(4-Chlorophenyl)morpholine
1-Fluoro-4-nitrobenzene
4-Chloronitrobenzene
4-Phenylmorpholine
morpholine
4-Bromoaniline
4-acetamido-N-[(3-iodo-4-methoxyphenyl)methylideneamino]benzamide

DownStream

4-Morpholin-4-yl-benzenethiol
4-(4-Isothiocyanatophenyl)morpholine
4-(morpholin-4-yl)benzenediazonium tetrafluoroborate
1-allyl-3-(4-Morpholinophenyl)thiourea
2-CHLORO-N-(4-MORPHOLIN-4-YL-PHENYL)-ACETAMIDE
Phenol,2-[[[4-(4-morpholinyl)phenyl]imino]methyl]-
6-methyl-2-(4-morpholin-4-ylanilino)pyridine-3-carboxylic acid
(5Z)-5-benzylidene-2-(4-methoxyphenyl)-3-(4-morpholin-4-ylphenyl)imidazol-4-one
(5Z)-2-(4-methoxyphenyl)-5-[(4-methoxyphenyl)methylidene]-3-(4-morpholin-4-ylphenyl)imidazol-4-one
4-(4-isocyanatophenyl)morpholine

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Synthesis and spectral characterization of Schiff base complexes of Cu(II), Co(II), Zn(II) and VO(IV) containing 4-(4-aminophenyl)morpholine derivatives: antimicrobial evaluation and anticancer studies.

Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 117 , 87-94, (2014)

Metal(II) chelates of Schiff bases derived from the condensation of 4-morpholinoaniline with substituted salicylaldehyde have been prepared and characterized by (1)H NMR, IR, electronic, EPR, and magn...

Electrochemical method for the synthesis of disulfides of 2-(benzo[d]thiazol(or oxazol)-2-ylamino)-5-morpholinobenzenethiol.

J. Org. Chem. 78(10) , 5018-21, (2013)

Electrochemical synthesis of two new disulfides of 2-(benzo[d]thiazol(or oxazol)-2-ylamino)-5-morpholinobenzene thiols was carried out via the electrooxidation of 4-morpholinoaniline in the presence o...

Synthesis of novel quinolone and quinoline-2-carboxylic acid (4-morpholin-4-yl-phenyl)amides: a late-stage diversification approach to potent 5HT1B antagonists.

Bioorg. Med. Chem. 15(2) , 939-50, (2007)

Multiparallel amenable syntheses of 6-methoxy-8-amino-4-oxo-1,4-dihydroquinoline-2-carboxylic acid-(4-morpholin-4-yl-phenyl)amides (I) and 4-amino-6-methoxy-8-(4-methyl-piperazin-1-yl)-quinoline-2-car...

4-Morpholinoaniline-d8
2-amino-4-morpholinoaniline
3-BROMO-4-MORPHOLINOANILINE
3-Fluoro-4-morpholinoaniline
3-chloro-4-morpholinoaniline
2-fluoro-4-morpholinoaniline
1-(3-Aminophenyl)-3-bromopropan-2-one
(R)-6,7-Dibromo-1,2,3,4-tetrahydronaphthalen-1-amine
N-[(E)-(2-hydroxyphenyl)methylideneamino]-4,7-dimethoxy-1H-indole-2-carboxamide
2-Heptyl-3-hydroxy-4H-chromene-4-thione
(3S)-3-Amino-3-(dimethyl-1,3-thiazol-5-yl)propanamide
3-(Benzyl(ethyl)amino)propane-1-sulfonyl chloride
(2Z)-5-(4-methoxybenzyl)-2-[(4-methylphenyl)imino]-1,3-thiazolidin-4-one
2-(((4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)thio)methyl)-3H-spiro[benzo[h]quinazoline-5,1'-cyclohexan]-4(6H)-one
N-(4-amino-2-((2-((2,5-dimethylphenyl)amino)-2-oxoethyl)thio)-6-oxo-1,6-dihydropyrimidin-5-yl)furan-2-carboxamide
6-(4-(Dimethylamino)phenyl)-4-imino-3-(3-(trifluoromethyl)phenyl)-1,3,7-trihydro-5,7-diazaquinazoline-2,8-dione

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