(3S,4S)-TERT-BUTYL 3-(BENZYLAMINO)-4-HYDROXYPYRROLIDINE-1-CARBOXYLATE

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Names

[ CAS No. ]:
252574-03-1

[ Name ]:
(3S,4S)-TERT-BUTYL 3-(BENZYLAMINO)-4-HYDROXYPYRROLIDINE-1-CARBOXYLATE

[Synonym ]:
rac-trans-3-benzylamino-4-hydroxy-pyrrolidine-1-carboxylic acid tert-butyl ester

Chemical & Physical Properties

[ Density]:
1.16

[ Boiling Point ]:
424.6ºC at 760 mmHg

[ Molecular Formula ]:
C16H24N2O3

[ Molecular Weight ]:
292.37300

[ Flash Point ]:
210.6ºC

[ Exact Mass ]:
292.17900

[ PSA ]:
61.80000

[ LogP ]:
2.08520

[ Vapour Pressure ]:
5.77E-08mmHg at 25°C

[ Index of Refraction ]:
1.564

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • (3S,4S)-3-benzylamino-4-hydroxy-pyrrolidine-1-carboxylic acid tert-butyl ester (+)-mandelic acid salt
  • Di-tert-butyl dicarbonate
  • tert-Butyl carbamate
  • N-Boc-3-pyrroline
  • 3-Boc-6-oxa-3-aza-bicyclo[3.1.0]hexane

DownStream

  • tert-butyl (3S,4S)-3-amino-4-hydroxypyrrolidine-1-carboxylate

Related Compounds

  • 3-[1-(Aminomethyl)cyclobutyl]-4-bromophenol
  • 1-(2-Bromo-5-methoxyphenyl)cyclobutan-1-amine
  • 2-Bromo-4-chloro-1-(4-isopropyl-phenyl)-butan-1-one
  • 1-(2-Bromo-6-methoxyphenyl)cyclobutan-1-amine
  • (6-fluoro-1H-indol-3-yl)methanethiol
  • Methyl 2-amino-3-(5-fluoro-2-methoxyphenyl)propanoate
  • 2-(Dimethoxymethyl)-7-methyl-1,8-naphthyridine
  • Methyl 3-amino-2-(4-tert-butylphenyl)propanoate
  • Methyl 4-amino-3-(1,3-dioxaindan-5-yl)butanoate
  • 1-[(4,6-Dichloropyridin-3-yl)methyl]piperazine
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