2,2-dichloro-N-(2-ethoxyethyl)-N-[[4-(4-nitrophenoxy)phenyl]methyl]acetamide

Names

[ CAS No. ]:
25287-60-9

[ Name ]:
2,2-dichloro-N-(2-ethoxyethyl)-N-[[4-(4-nitrophenoxy)phenyl]methyl]acetamide

[Synonym ]:
Chlorophenoxamide ethyl ether
Etofamida [INN-Spanish]
dichloro-acetic acid-{(2-ethoxy-ethyl)-[4-(4-nitro-phenoxy)-benzyl]-amide}
Etofamidum [INN-Latin]
N-(2-ethoxyethyl)-N-<4-(4-nitrophenoxy) benzyl> dichloroacetamide
Kitnosil
Ethylchlordiphene
Etofamide (INN)
Dichlor-essigsaeure-{(2-aethoxy-aethyl)-[4-(4-nitro-phenoxy)-benzyl]-amid}
Kitnos
Eticlordifene
Etofamide

Chemical & Physical Properties

[ Density]:
1.33g/cm3

[ Boiling Point ]:
536.3ºC at 760mmHg

[ Molecular Formula ]:
C19H20Cl2N2O5

[ Molecular Weight ]:
427.27900

[ Flash Point ]:
278.1ºC

[ Exact Mass ]:
426.07500

[ PSA ]:
84.59000

[ LogP ]:
5.07910

[ Vapour Pressure ]:
1.42E-11mmHg at 25°C

[ Index of Refraction ]:
1.581

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AB6568000
CHEMICAL NAME :
Acetamide, 2,2-dichloro-N-(2-ethoxyethyl)-N-(p-(p-nitrophenoxy)b enzyl)-
CAS REGISTRY NUMBER :
25287-60-9
BEILSTEIN REFERENCE NO. :
2918322
LAST UPDATED :
199612
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C19-H20-Cl2-N2-O5
MOLECULAR WEIGHT :
427.31

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GMIPAX Giornale di Malattie Infettive e Parassitarie. Journal of Infectious and Parasitic Diseases. (Societa Italiana per lo studio delle Malattie Infettive e Parassitarie, Via Appiani, 5, 20121 Milan, Italy) V.1- 1949- Volume(issue)/page/year: 10,850,1958
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GMIPAX Giornale di Malattie Infettive e Parassitarie. Journal of Infectious and Parasitic Diseases. (Societa Italiana per lo studio delle Malattie Infettive e Parassitarie, Via Appiani, 5, 20121 Milan, Italy) V.1- 1949- Volume(issue)/page/year: 10,850,1958
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FRPPAO Farmaco, Edizione Pratica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 27,585,1972
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FRPPAO Farmaco, Edizione Pratica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 27,585,1972

Safety Information

[ HS Code ]:
2924299090

Synthetic Route

Precursor & DownStream

Precursor

  • Dichloroacetyl chloride

DownStream

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%