3-Glycidoxypropyltrimethoxysilane

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Names

[ CAS No. ]:
2530-83-8

[ Name ]:
3-Glycidoxypropyltrimethoxysilane

[Synonym ]:
Glycidoxypropyl Trimethoxy Silane
Silane, trimethoxy[3-(oxiranylmethoxy)propyl]-
Z 6040
[3-(Glycidyloxy)propyl]trimethoxysilane
UNII:5K9X9X899R
Silane, [3-(2,3-epoxypropoxy)propyl]trimethoxy-
3-GlycidyloxypropyltriMethoxysilane
Y 4087
DZ 6040
KBM 430
silquest A187 silane
Silane, trimethoxy[3- (oxiranylmethoxy)propyl]-
γ-Glycidoxypropyltrimethoxysilane
[γ-(Glycidyloxy)propyl]trimethoxysilane
Trimethoxy[3-(oxiran-2-ylmethoxy)propyl]silane
Pivadorm
(γ-Glycidoxypropyl)trimethoxysilane
gamma-Glycidoxypropyltrimethoxysilane
Trimethoxy(3-(oxiran-2-ylmethoxy)propyl)silane
EINECS 219-784-2
NUCA 187
MFCD00005144
KBM 403
A 187
CG6720
3-Glycidoxypropyltrimethoxysilane
Trimethoxy[3-(2-oxiranylmethoxy)propyl]silane
[[3-(Trimethoxysilyl)propoxy]methyl]oxirane
GLYMO
Glycidyl 3-Trimethoxysilylpropyl Ether

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
299.4±0.0 °C at 760 mmHg

[ Melting Point ]:
-50°C

[ Molecular Formula ]:
C9H20O5Si

[ Molecular Weight ]:
236.338

[ Flash Point ]:
81.9±22.2 °C

[ Exact Mass ]:
236.108002

[ PSA ]:
49.45000

[ LogP ]:
0.28

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.436

[ Storage condition ]:
2-8°C

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VV4025000
CHEMICAL NAME :
Silane, 3-(2,3-epoxypropoxy)propyltrimethoxy-
CAS REGISTRY NUMBER :
2530-83-8
LAST UPDATED :
199710
DATA ITEMS CITED :
12
MOLECULAR FORMULA :
C9-H20-O5-Si
MOLECULAR WEIGHT :
236.38
WISWESSER LINE NOTATION :
T3OTJ B1O3-SI-O1&O1&O1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Open irritation test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
22600 uL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
5300 mg/m3/4H
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - lacrimation Nutritional and Gross Metabolic - weight loss or decreased weight gain
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
3970 uL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
119 mg/m3/6H/4W-I
TOXIC EFFECTS :
Nutritional and Gross Metabolic - weight loss or decreased weight gain

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
100 ug/plate
REFERENCE :
TSCAT* Office of Toxic Substances Report. (U.S. Environmental Protection Agency, Office of Toxic Substances, 401 M St., SW, Washington, DC 20460) Volume(issue)/page/year: OTS215156 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - T0269 No. of Facilities: 142 (estimated) No. of Industries: 3 No. of Occupations: 3 No. of Employees: 247 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - T0269 No. of Facilities: 4854 (estimated) No. of Industries: 40 No. of Occupations: 60 No. of Employees: 68889 (estimated) No. of Female Employees: 12321 (estimated)

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H318

[ Precautionary Statements ]:
P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R21;R36/38

[ Safety Phrases ]:
S28A-S26

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
2

[ RTECS ]:
VV4025000

[ Packaging Group ]:
III

[ HS Code ]:
29310095

Synthetic Route

Precursor & DownStream

Precursor

  • Allyl glycidyl ether
  • Trimethoxysilane

DownStream

  • [dihydroxy-[3-(oxiran-2-ylmethoxy)propyl]silyl]oxy-dihydroxy-[3-(oxiran-2-ylmethoxy)propyl]silane
  • 1,1,3,5,5-pentamethoxy-1,3,5-tris(3-(oxiran-2-ylmethoxy)propyl)trisiloxane

Customs

[ HS Code ]: 29310095

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