UNII:0514MAW53A
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Names
[ CAS No. ]:
25311-71-1
        
[ Name ]:
 UNII:0514MAW53A
        
[Synonym ]:
                
                pyrfon
                
                
            
                
                1-methylethyl 2-[[ethoxy[(1-methylethyl)amino]phosphinothioyl]oxy]benzoate
                
                
            
                
                Amidocid
                
                
            
                
                Amaze
                
                
            
                
                O-ethyl O-(2-isopropoxycarbonyl-phenyl-isopropyl) phosphoramidothioate
                
                
            
                
                ISOFENPHOS
                
                
            
                
                Benzoic acid, 2-[[ethoxy[(1-methylethyl)amino]phosphinothioyl]oxy]-, 1-methylethyl ester
                
                
            
                
                EINECS 246-814-1
                
                
            
                
                Pryfon
                
                
            
                
                (RS)-(O-ethyl O-2-isopropoxycarbonylphenyl isopropylphosphoramidothioate)
                
                
            
                
                [14C]-Isofenphos
                
                
            
                
                propan-2-yl 2-{[ethoxy(propan-2-ylamino)phosphorothioyl]oxy}benzoate
                
                
            
                
                Isopropyl 2-{[ethoxy(isopropylamino)phosphorothioyl]oxy}benzoate
                
                
            
                
                discus
                
                
            
                
                isopropyl (RS)-O-[ethoxy(isopropylamino)phosphinothioyl]salicylate
                
                
            
                
                propan-2-yl 2-{[(Ξ)-P-ethoxy-N-propan-2-ylphosphoramidothioyl]oxy}benzoate
                
                
            
                
                AMAZE(R)
                
                
            
                
                40sd
                
                
            
                
                MFCD00041805
                
                
            
                
                OFTANOL
                
                
            
                
                UNII:0514MAW53A
                
                
            
                
                le-mat
                
                
            
                
                O-ethyl-O-2-isopropoxycarbonylphenyl-N-isopropyl phosphoroamidothioate
                
                
            
                
                isophenphos
                
                
                
                
    
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
            
[ Boiling Point ]:
411.5±47.0 °C at 760 mmHg
            
[ Melting Point ]:
Less than -12ºC
            
[ Molecular Formula ]:
C15H24NO4PS
            
[ Molecular Weight ]:
345.394
            
[ Flash Point ]:
202.7±29.3 °C
            
[ Exact Mass ]:
345.116364
            
[ PSA ]:
98.69000
            
[ LogP ]:
4.12
            
[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C
            
[ Index of Refraction ]:
1.528
            
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- VO4395500
- CHEMICAL NAME :
- Salicylic acid, isopropyl ester, O-ester with O-ethyl isopropylphosphoramidothioate
- CAS REGISTRY NUMBER :
- 25311-71-1
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 10
- MOLECULAR FORMULA :
- C15-H24-N-O4-P-S
- MOLECULAR WEIGHT :
- 345.43
- WISWESSER LINE NOTATION :
- 1Y1&OVR DOPS&O2&MY1&1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 28 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85ARAE "Agricultural Chemicals," Thomson, W.T., 4 vols., Fresno, CA, Thomson Publications, 1976/77 revision Volume(issue)/page/year: 1,118,1977
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 144 mg/m3/4H
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85JFAN "Agrochemicals Handbook," with updates, Hartley, D., and H. Kidd, eds., Nottingham, Royal Soc. of Chemistry, 1983-86 Volume(issue)/page/year: A236,1983
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 188 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- SPEADM Special Publication of the Entomological Society of America. (4603 Calvert Rd., College Park, MD 20740) Volume(issue)/page/year: 78-1,39,1978
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 91300 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85DPAN "Wirksubstanzen der Pflanzenschutz und Schadlingsbekampfungsmittel," Perkow, W., Berlin, Verlag Paul Parey, 1971-1976 Volume(issue)/page/year: -,-,1971/1976
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 162 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094) Volume(issue)/page/year: -,C173,1991
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Bird - chicken
- DOSE/DURATION :
- 3 mg/kg
- TOXIC EFFECTS :
- Behavioral - tremor Behavioral - muscle weakness Gastrointestinal - changes in structure or function of salivary glands
- REFERENCE :
- BECTA6 Bulletin of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1966- Volume(issue)/page/year: 33,386,1984
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Bird - quail
- DOSE/DURATION :
- 13 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea
- REFERENCE :
- EESADV Ecotoxicology and Environmental Safety. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1977- Volume(issue)/page/year: 8,551,1984 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2240 mg/kg/8W-I
- TOXIC EFFECTS :
- Liver - other changes Biochemical - Metabolism (Intermediary) - other proteins
- REFERENCE :
- IJEBA6 Indian Journal of Experimental Biology. (Publications & Information Directorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963- Volume(issue)/page/year: 21,684,1983 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989
Safety Information
[ Symbol ]:
                
                
                GHS02, GHS07
            
[ Signal Word ]: 
Danger
            
[ Hazard Statements ]:
 H225-H302 + H312 + H332-H319-H412
            
[ Precautionary Statements ]:
 P210-P273-P280-P305 + P351 + P338
            
[ Personal Protective Equipment ]:
 Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
            
[ Hazard Codes ]:
 T: Toxic;N: Dangerous for the environment;
            
[ Risk Phrases ]:
 24/25-50/53
            
[ Safety Phrases ]:
 S36/37-S45-S60-S61
            
[ RIDADR ]: 
3018
            
[ RTECS ]: 
VO4395500
            
[ Packaging Group ]:
 I
            
[ Hazard Class ]:
6.1(a)
            
[ HS Code ]:
 2929909012
            
Customs
[ HS Code ]: 2929909012
[ Summary ]: 
2929909012 isopropyl 2-((ethoxy(isopropylamino)phosphorothioyl)oxy)benzoate