Urea,N'-(4-methoxyphenyl)-N-methyl-N-nitroso-

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Names

[ CAS No. ]:
25355-59-3

[ Name ]:
Urea,N'-(4-methoxyphenyl)-N-methyl-N-nitroso-

[Synonym ]:
N'-(4-methoxyphenyl)-N-methyl-N-nitroso-urea
3-<4-Methoxy-phenyl>1-methyl-1-nitroso-harnstoff
Urea,N'-(4-methoxyphenyl)-N-methyl-N-nitroso
1-(p-Methoxyphenyl)-3-methyl-3-nitrosourea
N-Methyl-N'-(p-methoxyphenyl)-N-nitrosourea
N-Methyl-N'-(4-methoxyphenyl)-N-nitrosourea
N-(4-Methoxy-phenyl)-N'-methyl-N'-nitroso-harnstoff
Urea,1-(p-methoxyphenyl)-3-methyl-3-nitroso

Chemical & Physical Properties

[ Density]:
1.24g/cm3

[ Molecular Formula ]:
C9H11N3O3

[ Molecular Weight ]:
209.20200

[ Exact Mass ]:
209.08000

[ PSA ]:
71.00000

[ LogP ]:
1.91330

[ Index of Refraction ]:
1.557

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YT6452000
CHEMICAL NAME :
Urea, 1-(p-methoxyphenyl)-3-methyl-3-nitroso-
CAS REGISTRY NUMBER :
25355-59-3
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C9-H11-N3-O3
MOLECULAR WEIGHT :
209.23
WISWESSER LINE NOTATION :
ONN1&VMR DO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
621 mg/kg/7W-I
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Gastrointestinal - tumors Skin and Appendages - tumors

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
33500 pmol/plate
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 39,5147,1979

Synthetic Route

Precursor & DownStream

Precursor

  • 3-(4-methoxyphenyl)-1-methyl-urea
  • p-Anisidine

DownStream

  • p-Anisidine

Related Compounds

  • 3-(4-methoxyphenyl)-1-methyl-1-(2-methyl-1-methylsulfanylpropyl)urea
  • Urea,N'-(4-chlorophenyl)-N-methyl-N-nitroso-
  • UREA, N'-(4-METHOXYPHENYL)-N,N-DIMETHYL-
  • 1-(p-Acetylphenyl)-3-methyl-3-nitrosourea
  • 1,1-dibenzyl-3-(4-methoxyphenyl)urea
  • Urea, N'-2-anthracenyl-N-methyl-N-nitroso-
  • 2-{[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)pyridin-2-yl]formamido}-3,3,3-trifluoropropanoic acid
  • 7-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanoyl]-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyrazine-6-carboxylic acid
  • 2-(N-benzyl-1-{1-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)ethyl]-1H-imidazol-4-yl}formamido)acetic acid
  • 2-{N-benzyl-1-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)bicyclo[2.2.1]heptan-2-yl]formamido}acetic acid
  • 4-({1-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclopropyl}formamido)-2-methylbut-2-enoic acid
  • 2-{2-[(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-(methylsulfanyl)butanamido]cyclopentyl}acetic acid
  • 2-{2-[(2R)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-(methylsulfanyl)butanamido]cyclopentyl}acetic acid
  • rac-(3R,4R)-1-{2-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]acetyl}-4-methylpyrrolidine-3-carboxylic acid
  • 4-[3-(dimethylamino)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanamido]-2-methoxybutanoic acid
  • 2-[N-benzyl-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-methylbutanamido]acetic acid
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