Levothyroxine sodium

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Names

[ CAS No. ]:
25416-65-3

[ Name ]:
Levothyroxine sodium

[Synonym ]:
Levothyroxine SodiuM,USP
acute
L-THYROXIN SODIUM
L-THYROXINE SODIUM,HYDRATE
SODIUM LEVOTHYROXINE,HYDRATE
Sodium Levothyroxine
Sodium (2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoate hydrate (1:1:1)
L-thyroxine sodium
L-Thyroxine sodium xhydrate
L-THYROXINE SODIUM SALT
EINECS 200-221-4
Levothyroxine sodium hydrate
L-THYROXINE SODIUM SALT,HYDRATE
L-Thyroxine sodium salt hydrate
MFCD06408007
L-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, sodium salt, hydrate (1:1:1)
LEVOTHYROXINESODIUM,HYDRATE,BP

Chemical & Physical Properties

[ Boiling Point ]:
576.3ºC at 760 mmHg

[ Melting Point ]:
207 °C

[ Molecular Formula ]:
C15H12I4NNaO5

[ Molecular Weight ]:
816.867

[ Flash Point ]:
302.3ºC

[ Exact Mass ]:
816.679138

[ PSA ]:
95.61000

[ LogP ]:
3.92290

[ Water Solubility ]:
0.15 g/L (25 ºC)

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R20/21

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

Articles

Impact of hydration state and molecular oxygen on the chemical stability of levothyroxine sodium.

Pharm. Dev. Technol. 20(3) , 314-9, (2015)

Levothyroxine sodium is an important medication used primarily for treating patients with hypothyroidism. Levothyroxine sodium tablets have been recalled many times since their 1955 introduction to th...


More Articles


Related Compounds

  • Levothyroxine sodium
  • Levothyroxine sodium
  • Levothyroxine Sodium Impurity 13
  • Levothyroxine Sodium Impurity 12
  • Levothyroxine acyl glucuronide
  • Levothyroxine Related Compound (N-Acetyl 3,5-diiodo-L-tyrosine Methyl Ester)