2-AMINO-4,6-DINITROTOLUENE

Names

[ Name ]:
2-AMINO-4,6-DINITROTOLUENE

[Synonym ]:
(1S)-2,3-dihydro-1H-inden-1-ol
(S)-2,3-dihydro-1H-inden-1-ol
(1S)-Indan-1-ol
MFCD00064165
(1S)-1-Indanol
1H-Inden-1-ol, 2,3-dihydro-, (1S)-

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
255.1±9.0 °C at 760 mmHg

[ Melting Point ]:
69-73ºC

[ Molecular Formula ]:
C₉H₁₀O

[ Molecular Weight ]:
134.175

[ Flash Point ]:
89.2±11.0 °C

[ Exact Mass ]:
134.073166

[ PSA ]:
20.23000

[ LogP ]:
1.49

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.609

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
R22;R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2906299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

2,3-Dihydro-1H-inden-1-ol
1-Indanone
acetic acid,(1S)-2,3-dihydro-1H-inden-1-ol
isopropyl butyrate
Indene
Indane
Diphenyl Methyl Chlorosilane
Chlorotriethylsilane
Chlorodimethylphenylsilane
Isopropenyl acetate

DownStream

1-Indanone
(R)-(-)-1-INDANOL
2,3-Dihydro-1H-inden-1-ol

Customs

[ HS Code ]: 2906299090

[ Summary ]:
2906299090 other aromatic alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

Articles

Naturally occurring variants of human aldo-keto reductases with reduced in vitro metabolism of daunorubicin and doxorubicin.

J. Pharmacol. Exp. Ther. 335 , 533-545, (2010)

Doxorubicin (DOX) and daunorubicin (DAUN) are effective anticancer drugs; however, considerable interpatient variability exists in their pharmacokinetics. This may be caused by altered metabolism by n...

Stereochemical sensitivity of the human UDP-glucuronosyltransferases 2B7 and 2B17.

J. Med. Chem. 49 , 1818-27, (2006)

A set of 28 enantiomers comprising rigid and flexible secondary alcohols was synthesized by the asymmetric Corey-Bakshi-Shibata reduction. The enantiomerically pure alcohols were subjected to enzymati...

Determination of the single component and competitive adsorption isotherms of the 1-indanol enantiomers by the inverse method.

J. Chromatogr. A. 1005(1-2) , 35-49, (2003)

The inverse method of isotherm determination consists in calculating the numerical values of the coefficients of an isotherm model that give a set of chromatographic profiles in best possible agreemen...

2-AMINO-4,6-DINITROTOLUENE
N-acetyl-2-amino-4,6-dinitrotoluene
2-Amino-4,6-dimethylpyrimidine
2-AMINO-4,6-DIFLUOROPHENOL
2-AMINO-4,6-BIS(ETHYLAMINO)-1,3,5-TRIAZINE
2-amino-4,6-bis(2,2-diphenylhydrazinyl)benzene-1,3,5-tricarbonitrile
rac-tert-butyl 2-[(1R,3R)-3-(aminomethyl)-2,2-dimethylcyclopropyl]piperidine-1-carboxylate
(2S,4R)-1-[(2S)-2-[(2-chloroacetyl)amino]-3,3-dimethyl-butanoyl]-4-hydroxy-N-[[4-(4-methylthiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
5-(Bromomethyl)-3-tert-butyl-1,2,4-thiadiazole
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
(4-Methyl-tetrahydro-furan-2-yl)-methanol
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
(3S)-3-hydroxy-3-(5-propylthiophen-2-yl)propanoic acid