1-Ethynyl-3-fluorobenzene

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Names

[ CAS No. ]:
2561-17-3

[ Name ]:
1-Ethynyl-3-fluorobenzene

[Synonym ]:
1-Ethynyl-3-fluorobenzene
1-(1-ethynyl)-3-fluorobenzene
Benzene, 1-ethynyl-3-fluoro-
3-F-phenylacetylene
(3-fluorophenyl)acetylene
1-fluoro-3-ethynylbenzene
3-FC6H4CCH
MFCD03093798

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
148.7±23.0 °C at 760 mmHg

[ Molecular Formula ]:
C8H5F

[ Molecular Weight ]:
120.124

[ Flash Point ]:
26.2±15.7 °C

[ Exact Mass ]:
120.037529

[ LogP ]:
2.45

[ Vapour Pressure ]:
5.3±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.516

MSDS

Safety Information

[ Symbol ]:

GHS02, GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H226-H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R10;R36/37/38

[ Safety Phrases ]:
S16-S26-S36

[ RIDADR ]:
UN 1993 3/PG 3

[ WGK Germany ]:
3

[ HS Code ]:
2903999090

Synthetic Route

Precursor & DownStream

Precursor

  • [(3-Fluorophenyl)ethynyl](trimethyl)silane
  • (Z)-1-(2-bromovinyl)-3-fluorobenzene
  • 1-(3-Fluorophenyl)ethanol
  • 3-Fluorostyrene
  • 3-Fluorophenylmagnesium bromide solution
  • 1-Bromo-3-fluorobenzene
  • Fluorobenzene

DownStream

  • 3-Fluorobenzoic acid
  • 1-(3-Fluorophenyl)ethanone
  • 3-Fluorostyrene
  • 4-(3-FLUOROPHENYL)THIAZOL-2-AMINE
  • 1-fluoro-3-(2-phenylethynyl)benzene
  • 3-Fluorophenethylalcohol
  • (3-Fluorophenyl)acetaldehyde
  • 3-Nitroaniline
  • Isobutylboronic acid pinacol ester

Customs

[ HS Code ]: 2903999090

[ Summary ]:
2903999090 halogenated derivatives of aromatic hydrocarbons VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles

N-trifluoromethylthiosaccharin: an easily accessible, shelf-stable, broadly applicable trifluoromethylthiolating reagent.

Angew. Chem. Int. Ed. Engl. 53(35) , 9316-20, (2014)

A new, electrophilic trifluoromethylthiolating reagent, N-trifluoromethylthiosaccharin, was developed and can be synthesized in two steps from saccharin within 30 minutes. N-trifluoromethylthiosacchar...

Copper-catalyzed amine-alkyne-alkyne addition reaction: an efficient method for the synthesis of gamma,delta-alkynyl-beta-amino acid derivatives.

Chemistry 15(43) , 11668-74, (2009)

A simple and efficient method for the synthesis of gamma,delta-alkynyl-beta-amino acid derivatives by a copper-catalyzed three-component amine-alkyne-alkyne addition reaction was developed. Various ga...

Gold film-catalysed benzannulation by microwave-assisted, continuous flow organic synthesis (MACOS).

.PubMed ID

Methodology has been developed for laying down a thin gold-on-silver film on the inner surface of glass capillaries for the purpose of catalysing benzannulation reactions. The cycloaddition precursors...


More Articles


Related Compounds

  • 1-Ethynyl-3,4-fluorobenzene
  • 1-ethynyl-3-isopropoxy-benzene
  • 1-ethynyl-3-(prop-2-enoxymethyl)benzene
  • 1-ethynyl-3-methoxy-2-(methoxymethoxy)benzene
  • 1-Ethynyl-3-(trifluoromethoxy)-benzene
  • 1-ethynyl-3-[4-[4-(3-ethynylphenoxy)phenyl]sulfonylphenoxy]benzene
  • 3-{[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-1,3-thiazol-4-yl]formamido}-2-hydroxypropanoic acid
  • 4-[(2R)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-methylbutanamido]-2-methylbutanoic acid
  • 4-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylbutanamido]-2-methylbutanoic acid
  • 4-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-N,2-dimethylbutanamido]butanoic acid
  • 2-{[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cycloheptyl]formamido}acetic acid
  • (2S)-2-{[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]formamido}butanoic acid
  • 1-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-methoxypropanoyl]pyrrolidine-3-carboxylic acid
  • 1,1-Difluoro-2-methyl-3-(1,3-thiazol-5-yl)propan-2-amine
  • 3-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-5-methoxypentanamido]propanoic acid
  • 3-(2-{1-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclobutyl}acetamido)propanoic acid
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