Acetamide,N-[5-(5-nitro-2-furanyl)-1,3,4-thiadiazol-2-yl]-

Suppliers

Names

[ CAS No. ]:
2578-75-8

[ Name ]:
Acetamide,N-[5-(5-nitro-2-furanyl)-1,3,4-thiadiazol-2-yl]-

[Synonym ]:
N-acetyl-tiafur
C 132
N-acetyl-thiafur
N-acetyl-furidiazine

Chemical & Physical Properties

[ Density]:
1.605g/cm3

[ Molecular Formula ]:
C8H6N4O4S

[ Molecular Weight ]:
254.22300

[ Exact Mass ]:
254.01100

[ PSA ]:
142.08000

[ LogP ]:
2.26090

[ Index of Refraction ]:
1.66

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AC6500000
CHEMICAL NAME :
Acetamide, N-(5-(5-nitro-2-furyl)-1,3,4-thiadiazol-2-yl)-
CAS REGISTRY NUMBER :
2578-75-8
LAST UPDATED :
199612
DATA ITEMS CITED :
8
MOLECULAR FORMULA :
C8-H6-N4-O4-S
MOLECULAR WEIGHT :
254.24
WISWESSER LINE NOTATION :
T5OJ BNW E- ET5NN DSJ CMV1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
33 gm/kg/40W-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Gastrointestinal - tumors Skin and Appendages - tumors
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
80 gm/kg/46W-C
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria Gastrointestinal - tumors Blood - leukemia

MUTATION DATA

TYPE OF TEST :
DNA repair
TEST SYSTEM :
Bacteria - Escherichia coli
DOSE/DURATION :
500 nmol/well
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 34,2266,1974 *** REVIEWS *** TOXICOLOGY REVIEW CCSUDL Carcinogenesis--A Comprehensive Survey. (Raven Press, 1185 Ave. of the Americas, New York, NY 10036) V.1- 1976- Volume(issue)/page/year: 4,171,1978

Safety Information

[ HS Code ]:
2934999090

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 3-[10-(2-Naphthalenyl)-9-anthracenyl]-9-phenyl-9h-carbazole
  • N4-(2-(dimethylamino)ethyl)-2-methylpyrimidine-4,6-diamine
  • 4-Ethynylphthalonitrile
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 3-Bromo-4-chloro-alpha-(trifluoromethyl)benzyl Alcohol
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide