1,2:3,5-DI-O-ISOPROPYLIDENE-α-D-APIOSE

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Names

[ CAS No. ]:
25904-06-7

[ Name ]:
1,2:3,5-DI-O-ISOPROPYLIDENE-α-D-APIOSE

[Synonym ]:
1,2:5,6-DI-O-ISOPROPYLIDENE-A-D-APIOSE
1,2:3,5-di-O-isopropylidene-A-D-apiose
1,2:3,5-Di-O-isopropylidene

Chemical & Physical Properties

[ Density]:
1.22g/cm3

[ Boiling Point ]:
278.2ºC at 760 mmHg

[ Melting Point ]:
82ºC

[ Molecular Formula ]:
C₁₁H₁₈O₅

[ Molecular Weight ]:
230.25800

[ Flash Point ]:
107.1ºC

[ Exact Mass ]:
230.11500

[ PSA ]:
46.15000

[ LogP ]:
1.01590

[ Vapour Pressure ]:
0.00731mmHg at 25°C

[ Index of Refraction ]:
1.502

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Precursor & DownStream

Precursor

DownStream

Articles

Conformationally constrained analogues of diacylglycerol. 13. Protein kinase C ligands based on templates derived from 2,3-dideoxy-L-erythro(threo)-hexono-1,4-lactone and 2-deoxyapiolactone.

J. Med. Chem. 39 , 4912-4919, (1996)

In the present investigation, the last two possible modes of generating conformationally semirigid diacylglycerol (DAG) analogues embedded into five-membered ring lactones as templates III and IV are ...

1,2:3,5-Di-O-isopropylidene-alpha-D-xylofuranose
1,2,3,3'-di-O-isopropylidene-3-C-(hydroxymethyl)-α-D-erythrofuranose
(3aS,3bR,7aS,8aS)-2,2,5,5-tetramethyltetrahydro-3aH-[1,3]dioxolo[4',5':4,5]furo[3,2-d][1,3]dioxane
1,5-di-O-acetyl-2,3-O-isopropylidene-α-D-ribofuranose
6-O-Allyl-1,2:3,4-di-O-isopropylidene-α-D-galactopyranose
6-O-(imidazolylthiocarbonyl)-1,2:3,4-di-O-isopropylidene-α-D-galactopyranose
1,6-Dihydro-5-(2-hydroxyphenyl)-1-methyl-3-propyl-7H-pyrazolo[4,3-d]pyrimidin-7-one
1-(4,6-dimethylpyrimidin-2-yl)-3-methyl-4-[4-(prop-2-yn-1-yloxy)phenyl]-4,5-dihydro-1H-pyrazolo[3,4-b]pyridin-6-ol
2-{[4-(4-tert-butylphenyl)-5-cyano-6-oxo-1,6-dihydropyrimidin-2-yl]sulfanyl}-N-(2-methoxyphenyl)acetamide
2-((6-benzyl-4-oxo-3,4,5,6,7,8-hexahydropyrido[4,3-d]pyrimidin-2-yl)thio)-N-(3-chloro-4-methoxyphenyl)acetamide
2-({6-benzyl-4-oxo-3H,4H,5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl}sulfanyl)-N-(3-chloro-4-methylphenyl)acetamide
N-(3,5-dimethylphenyl)-2-((6-(4-methoxybenzyl)-4-oxo-3,4,5,6,7,8-hexahydropyrido[4,3-d]pyrimidin-2-yl)thio)acetamide
N-(2,3-dimethylphenyl)-2-((6-(4-methylbenzyl)-4-oxo-3,4,5,6,7,8-hexahydropyrido[4,3-d]pyrimidin-2-yl)thio)acetamide
2-((6-(benzo[d][1,3]dioxol-5-ylmethyl)-4-oxo-3,4,5,6,7,8-hexahydropyrido[4,3-d]pyrimidin-2-yl)thio)-N-(3,4-dimethylphenyl)acetamide
2-((6-(benzo[d][1,3]dioxol-5-ylmethyl)-4-oxo-3,4,5,6,7,8-hexahydropyrido[4,3-d]pyrimidin-2-yl)thio)-N-(2,3-dimethylphenyl)acetamide
2-((6-(benzo[d][1,3]dioxol-5-ylmethyl)-4-oxo-3,4,5,6,7,8-hexahydropyrido[4,3-d]pyrimidin-2-yl)thio)-N-(3,4-difluorophenyl)acetamide

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