4-Nonylphenol polyethoxylate

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Names

[ CAS No. ]:
26027-38-3

[ Name ]:
4-Nonylphenol polyethoxylate

[Synonym ]:
nonoxynol-4
NONOXINOLS
Alkylphenol ethoxylates: Nonylphenol-ethylene oxide condensate (Nonoxynol-9)
nonoxynol-2
Polyethylene Glycol Mono-4-nonylphenyl Ether n≈7.5
tergitol R(NP 10)
Conceptol
Novoxynol
Polyethylene Glycol Mono-4-nonylphenyl Ether n(=:)20
MFCD00134080
Tergitol7
n-9
Polyethylene Glycol Mono-4-nonylphenyl Ether n≈18
nonoxynol
np-9
nonoxynol-6
4-Nonylphenol polyethoxylate

Chemical & Physical Properties

[ Density]:
1.06

[ Boiling Point ]:
250ºC

[ Melting Point ]:
57-58ºC

[ Molecular Formula ]:
C28H50O8

[ Molecular Weight ]:
514.69200

[ Flash Point ]:
94ºC

[ Exact Mass ]:
514.35100

[ PSA ]:
84.84000

[ LogP ]:
3.87110

[ Index of Refraction ]:
1.4950-1.4990

[ Storage condition ]:
0-6°C

[ Water Solubility ]:
Miscible with water, with ethanol (96 per cent) and with vegetable oils.

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
MD0906000
CHEMICAL NAME :
Glycols, polyethylene, mono(p-nonylphenyl) ether
CAS REGISTRY NUMBER :
26027-38-3
LAST UPDATED :
199710
DATA ITEMS CITED :
15
WISWESSER LINE NOTATION :
/*O2*/ *9R D **Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
150 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2860 mg/kg/22D-I
TOXIC EFFECTS :
Liver - changes in liver weight Endocrine - changes in spleen weight Nutritional and Gross Metabolic - weight loss or decreased weight gain
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intrauterine
DOSE :
2500 ug/kg
SEX/DURATION :
female 1 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intrauterine
DOSE :
5 mg/kg
SEX/DURATION :
female 1 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea) Reproductive - Fertility - other measures of fertility
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intravaginal
DOSE :
50 mg/kg
SEX/DURATION :
female 1 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Maternal Effects - uterus, cervix, vagina Reproductive - Maternal Effects - other effects
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intravaginal
DOSE :
50 mg/kg
SEX/DURATION :
female 3 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea)
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intravaginal
DOSE :
1250 ug/kg
SEX/DURATION :
female 10 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Maternal Effects - uterus, cervix, vagina
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intravaginal
DOSE :
1 mg/kg
SEX/DURATION :
female 1 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)

MUTATION DATA

TYPE OF TEST :
Morphological transformation
TEST SYSTEM :
Rodent - mouse Fibroblast
DOSE/DURATION :
10 ppm
REFERENCE :
CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 3,553,1982 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M4862 No. of Facilities: 82021 (estimated) No. of Industries: 303 No. of Occupations: 188 No. of Employees: 842001 (estimated) NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - T0292 No. of Facilities: 3063 (estimated) No. of Industries: 12 No. of Occupations: 20 No. of Employees: 9425 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X8533 No. of Facilities: 30457 (estimated) No. of Industries: 190 No. of Occupations: 159 No. of Employees: 1297228 (estimated) No. of Female Employees: 863213 (estimated)

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H318-H412

[ Precautionary Statements ]:
P280-P301 + P312 + P330-P305 + P351 + P338 + P310

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
MD0906000

Related Compounds

  • 4-nonylphenol,trihydroxy(sulfanylidene)-λ5-phosphane
  • 4-Nonylphenol
  • 4-Nonylphenol, branched
  • 4-Nonylphenol branched ethoxylated
  • 4-nonylphenol,phosphoric acid
  • 4-nonylphenol
  • 2-(3-Azido-5-{[(tert-butoxy)carbonyl]amino}-2-methylphenyl)acetic acid
  • 3-(2-Chloro-4-hydroxyphenyl)-2,2-dimethylcyclopropane-1-carboxylic acid
  • 2-(2-Azidoethyl)-4,5,6,7-tetrahydro-1-benzothiophene
  • 1,3-Dimethyl-5-(methyl(piperidin-4-yl)amino)pyrimidine-2,4(1H,3H)-dione
  • 1-(2-ethoxy-2-methylpropyl)-4-methyl-1H-pyrazol-3-amine
  • 1-(4-bromo-3,3-dimethylbutyl)-1H-1,2,3,4-tetrazole
  • N-methyl-1-[(1-methyl-3-phenyl-1H-pyrazol-5-yl)methyl]cyclopropan-1-amine
  • tert-butyl N-[2-(4,5-difluoro-2-methoxyphenyl)-1-oxopropan-2-yl]-N-methylcarbamate
  • 2-(4-Bromo-3,3-dimethylbutyl)-1-methylpyrrolidine
  • 1-ethenyl-4-[(pyrrolidin-3-yl)methyl]-1H-pyrazole
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