2-HYDRAZINO-4-(4-AMINOPHENYL)THIAZOLE

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Names

[ CAS No. ]:
26049-71-8

[ Name ]:
2-HYDRAZINO-4-(4-AMINOPHENYL)THIAZOLE

Chemical & Physical Properties

[ Density]:
1.409g/cm3

[ Boiling Point ]:
435.5ºC at 760mmHg

[ Molecular Formula ]:
C9H10N4S

[ Molecular Weight ]:
206.26700

[ Flash Point ]:
217.2ºC

[ Exact Mass ]:
206.06300

[ PSA ]:
105.20000

[ LogP ]:
3.03240

[ Vapour Pressure ]:
8.73E-08mmHg at 25°C

[ Index of Refraction ]:
1.757

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XJ2880000
CHEMICAL NAME :
Thiazole, 4-(p-aminophenyl)-2-hydrazino-
CAS REGISTRY NUMBER :
26049-71-8
BEILSTEIN REFERENCE NO. :
0170828
LAST UPDATED :
199706
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C9-H10-N4-S
MOLECULAR WEIGHT :
206.29
WISWESSER LINE NOTATION :
T5N CSJ BMZ ER DZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
12 gm/kg/24W-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Gastrointestinal - tumors Skin and Appendages - tumors
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 30,897,1970
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
8000 mg/kg/46W-C
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Blood - leukemia
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 33,1593,1973

Safety Information

[ HS Code ]:
2934100090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • acetic acid-{N'-[4-(4-nitro-phenyl)-thiazol-2-yl]-hydrazide}

DownStream

Customs

[ HS Code ]: 2934100090

[ Summary ]:
2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

Related Compounds

  • 2-[[4-(4-aminophenyl)sulfonylphenyl]amino]-1H-pyrimidine-4,5,6-trione
  • 2-[4-[(4-aminophenyl)methyl]-7,10-bis(carboxymethyl)-1,4,7,10-tetrazacyclododec-1-yl]acetic acid
  • 2-[4-[(4-aminophenyl)methyl]piperazin-1-yl]ethyl (2S)-2-(6-methoxynaphthalen-2-yl)propanoate
  • 2-{4-[(4-aminophenyl)sulfonyl]phenyl}-1H-isoindole-1,3(2H)-dione
  • 2-[4-(4-aminophenyl)-1,3-thiazol-2-yl]guanidine
  • 2-[4-(4-aminophenyl)-1,3-oxazol-2-yl]guanidine