2-O-(P-NITROPHENYL)-ALPHA-D-N-ACETYLNEURAMINIC ACID

Names

[ CAS No. ]:
26112-88-9

[ Name ]:
2-O-(P-NITROPHENYL)-ALPHA-D-N-ACETYLNEURAMINIC ACID

[Synonym ]:
2-O-(P-NITROPHENYL)-α-D-N-ACETYLNEURAMINIC ACID

Chemical & Physical Properties

[ Density]:
1.61g/cm3

[ Boiling Point ]:
853.3ºC at 760 mmHg

[ Molecular Formula ]:
C₁₇H₂₂N₂O₁₁

[ Molecular Weight ]:
430.36300

[ Flash Point ]:
469.9ºC

[ Exact Mass ]:
430.12200

[ PSA ]:
211.60000

[ Vapour Pressure ]:
5.41E-31mmHg at 25°C

[ Index of Refraction ]:
1.644

MSDS

Safety Information

[ Symbol ]:

GHS06, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301-H311-H315-H319-H331-H335-H351

[ Precautionary Statements ]:
P261-P280-P301 + P310-P305 + P351 + P338-P311

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

methyl (4-nitrophenyl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-2-oxy-α-D-glycero-D-galacto-2-nonulopyranosid)onate
5-ACETAMINO-4-HYDROXY-2-(4-NITRO-PHENOXY)-6-(1,2,3-TRIHYDROXY-PROPYL)-TETRAHYDRO-PYRAN-2-CARBOXYLIC ACID METHYL ESTER
4-Nitrophenol
methyl 2-chloro-4,7,8,9-tetra-O-acetyl-N-acetyl-β-D-neuraminate
Sodium 4-nitrophenoxide
methyl 5-acetamido-4,7,8,9-tetra-O-acetyl-2-bromo-2,5-dideoxy-β-D-erythro-L-gluco-2-nonulopyranosonate
methyl (p-nitrophenyl 5-acetamido-4,7,8,9-tetra-O-acetyl-5-deoxy-3-O-(phenoxythiocarbonyl)-α-D-erythro-L-gluco-2-nonulopyranosid)onate
N-ACETYL-2-CHLORO-2-DEOXYNEURAMINIC ACID METHYL ESTER 4,7,8,9-TETRAACETATE

DownStream

Articles

Synthesis of p-nitrophenyl 5-acetamido-3,5-dideoxy-alpha-D-glycero-D-galacto-2-nonulopyranosid onic acid, a chromogenic substrate for sialidases.

Carbohydr. Res. 162(2) , 294-7, (1987)

Salmonella typhimurium neuraminidase acts with inversion of configuration.

Biochem. J. 296 ( Pt 2) , 291-2, (1993)

When the time course of the hydrolysis of identical solutions of p-nitrophenyl N-acetyl-alpha-D-neuraminide by Salmonella typhimurium neuraminidase is monitored by u.v. and by its optical rotation, th...

[2-(4-Methoxy-benzyl)-1-oxo-1,2,3,4-tetrahydro-isoquinolin-6-yl]-acetonitrile
4-Ethyl-2-pentylthiazole
5-Bromo-3-((5-hydroxypyridin-2-yl)amino)-1-methylpyridin-2(1h)-one
2-Bromo-6-(6-(1-(difluoromethyl)cyclopropyl)-1-oxo-3,4-dihydroisoquinolin-2(1h)-yl)benzaldehyde
2-Methyl-2-(1-oxo-1,2,3,4-tetrahydro-isoquinolin-6-yl)-propionaldehyde
2-(3-Bromo-phenyl)-6-dimethylamino-3,4-dihydro-2H-isoquinolin-1-one
6-(1-Chlorocyclopropyl)-2-(4-methoxybenzyl)-3,4-dihydroisoquinolin-1(2h)-one
(Z)-ethyl 3-(3-(dimethylamino)phenylamino)-2-(3-bromo-2-methylphenyl)acrylate
2-(4-(2-Aminoethyl)-1H-imidazol-1-yl)ethanol
[2-(4-Methoxy-benzyl)-1-oxo-1,2,3,4-tetrahydro-isoquinolin-6-yl]-acetic Acid Tert-Butyl Ester

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