2-O-(P-NITROPHENYL)-ALPHA-D-N-ACETYLNEURAMINIC ACID

Names

[ CAS No. ]:
26112-88-9

[ Name ]:
2-O-(P-NITROPHENYL)-ALPHA-D-N-ACETYLNEURAMINIC ACID

[Synonym ]:
2-O-(P-NITROPHENYL)-α-D-N-ACETYLNEURAMINIC ACID

Chemical & Physical Properties

[ Density]:
1.61g/cm3

[ Boiling Point ]:
853.3ºC at 760 mmHg

[ Molecular Formula ]:
C₁₇H₂₂N₂O₁₁

[ Molecular Weight ]:
430.36300

[ Flash Point ]:
469.9ºC

[ Exact Mass ]:
430.12200

[ PSA ]:
211.60000

[ Vapour Pressure ]:
5.41E-31mmHg at 25°C

[ Index of Refraction ]:
1.644

MSDS

Safety Information

[ Symbol ]:

GHS06, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301-H311-H315-H319-H331-H335-H351

[ Precautionary Statements ]:
P261-P280-P301 + P310-P305 + P351 + P338-P311

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

methyl (4-nitrophenyl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-2-oxy-α-D-glycero-D-galacto-2-nonulopyranosid)onate
5-ACETAMINO-4-HYDROXY-2-(4-NITRO-PHENOXY)-6-(1,2,3-TRIHYDROXY-PROPYL)-TETRAHYDRO-PYRAN-2-CARBOXYLIC ACID METHYL ESTER
4-Nitrophenol
methyl 2-chloro-4,7,8,9-tetra-O-acetyl-N-acetyl-β-D-neuraminate
Sodium 4-nitrophenoxide
methyl 5-acetamido-4,7,8,9-tetra-O-acetyl-2-bromo-2,5-dideoxy-β-D-erythro-L-gluco-2-nonulopyranosonate
methyl (p-nitrophenyl 5-acetamido-4,7,8,9-tetra-O-acetyl-5-deoxy-3-O-(phenoxythiocarbonyl)-α-D-erythro-L-gluco-2-nonulopyranosid)onate
N-ACETYL-2-CHLORO-2-DEOXYNEURAMINIC ACID METHYL ESTER 4,7,8,9-TETRAACETATE

DownStream

Articles

Synthesis of p-nitrophenyl 5-acetamido-3,5-dideoxy-alpha-D-glycero-D-galacto-2-nonulopyranosid onic acid, a chromogenic substrate for sialidases.

Carbohydr. Res. 162(2) , 294-7, (1987)

Salmonella typhimurium neuraminidase acts with inversion of configuration.

Biochem. J. 296 ( Pt 2) , 291-2, (1993)

When the time course of the hydrolysis of identical solutions of p-nitrophenyl N-acetyl-alpha-D-neuraminide by Salmonella typhimurium neuraminidase is monitored by u.v. and by its optical rotation, th...

2-{4-[(3-Fluorophenyl)methyl]piperazin-1-yl}-4-(trifluoromethyl)pyrimidine
2-{4-[(4-Fluorophenyl)methyl]piperazin-1-yl}-4-(trifluoromethyl)pyrimidine
1-benzyl-4-({4H,5H,6H-cyclopenta[d][1,3]thiazol-2-yl}methyl)piperazin-2-one
6-[4-[(3-Fluorophenyl)methyl]piperazin-1-yl]-N,N-dimethylpyridazin-3-amine
6-{4-[(4-fluorophenyl)methyl]piperazin-1-yl}-N,N-dimethylpyridazin-3-amine
2-{4-[(4-Fluorophenyl)methyl]piperazin-1-yl}-4-(pyrrolidin-1-yl)pyrimidine
4-{4-[(3-Fluorophenyl)methyl]piperazin-1-yl}-6-(pyrrolidin-1-yl)pyrimidine
N-(1-{thieno[2,3-d]pyrimidin-4-yl}piperidin-4-yl)cyclopropanesulfonamide
1-methyl-4-{4-[(1-{3-methyl-3H-imidazo[4,5-b]pyridin-2-yl}piperidin-4-yl)oxy]but-2-yn-1-yl}piperazine
4-(4-{4-[(4-Fluorophenyl)methyl]piperazin-1-yl}-6-methylpyrimidin-2-yl)morpholine

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