clofop

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Names

[ Name ]:
clofop

[Synonym ]:
2-[4-(4-chlorophenoxy)phenoxy]propanoic acid
rac-(2R)-2-[4-(4-chlorophenoxy)phenoxy]propanoic acid
Clofop [ISO]
LF 479
HCG 004
2-[4'-(4''-chlorophenoxy)phenoxy]-propionic acid
D-2-[p-(p-chlorophenoxy)phenoxy]propionic acid
2-(4-(4-Chlorophenoxy)phenoxy)propanoic acid
EINECS 255-626-9
MFCD00792461
(RS)-2-[4-(4-chlorophenoxy)phenoxy]propionic acid
fenofibric acid
D-2-[4-(4-chlorophenoxy)-phenoxy]-propionic acid

Chemical & Physical Properties

[ Density]:
1.306 g/cm3

[ Boiling Point ]:
431.9ºC at 760 mmHg

[ Molecular Formula ]:
C₁₅H₁₃ClO₄

[ Molecular Weight ]:
292.71400

[ Flash Point ]:
215ºC

[ Exact Mass ]:
292.05000

[ PSA ]:
55.76000

[ LogP ]:
3.98420

[ Vapour Pressure ]:
3.17E-08mmHg at 25°C

[ Index of Refraction ]:
1.584

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UE9518000

CHEMICAL NAME :: Propionic acid, 2-(p-(p-chlorophenoxy)phenoxy)-

CAS REGISTRY NUMBER :: 26129-32-8

LAST UPDATED :: 199706

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C15-H13-Cl-O4

MOLECULAR WEIGHT :: 292.73

WISWESSER LINE NOTATION :: QVY1&OR DOR DG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 4,326,1979

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 190 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 4,326,1979

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NPMDAD Nouvelle Presse Medicale. (Paris, France) V.1-11, 1972-82. Volume(issue)/page/year: 9,3737,1980

Safety Information

[ HS Code ]:
2918990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

4-Bromoanisole
1-Chloro-4-(4-methoxyphenoxy)benzene
4-Chlorophenol
4-(4-Chlorophenoxy)phenol
Ethyl (2S)-2-bromopropanoate

DownStream

Customs

[ HS Code ]: 2918990090

[ Summary ]:
2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%