Glycine,N,N-bis(2-chloroethyl)-, hydrochloride (6CI,7CI,8CI,9CI)
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Names
[ CAS No. ]:
2619-97-8
[ Name ]:
Glycine,N,N-bis(2-chloroethyl)-, hydrochloride (6CI,7CI,8CI,9CI)
[Synonym ]:
N,N-Bis(2-chloraethyl)formamid
N,N-Bis-(2-chlor-aethyl)-glycin,Hydrochlorid
N,N-bis-(2-chloro-ethyl)formamide
Ameisensaeure-[bis-(2-chlor-aethyl)-amid]
2-<Bis-(2-chlorethyl)-amino>-essigsaeure
N,N-bis-(2-chloro-ethyl)-glycine,hydrochloride
FORMAMIDE,N,N-BIS(2-CHLOROETHYL)
Chemical & Physical Properties
[ Density]:
1.314g/cm3
[ Boiling Point ]:
236ºC at 760 mmHg
[ Molecular Formula ]:
C6H12Cl3NO2
[ Molecular Weight ]:
236.52400
[ Flash Point ]:
96.5ºC
[ Exact Mass ]:
234.99300
[ PSA ]:
40.54000
[ LogP ]:
1.65260
[ Vapour Pressure ]:
0.0167mmHg at 25°C
[ Index of Refraction ]:
1.5
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- MB8480000
- CHEMICAL NAME :
- Glycine, N,N-bis(2-chloroethyl)-, hydrochloride
- CAS REGISTRY NUMBER :
- 2619-97-8
- LAST UPDATED :
- 199203
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C6-H11-Cl2-N-O2.Cl-H
- MOLECULAR WEIGHT :
- 236.54
- WISWESSER LINE NOTATION :
- QV1N2G2G &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intracerebral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 113 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949- Volume(issue)/page/year: 18,760,1966
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 15 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - active as anti-cancer agent
- REFERENCE :
- PHBUA9 Pharmaceutical Bulletin. (Tokyo, Japan) V.1-5, 1953-57. For publisher information, see CPBTAL. Volume(issue)/page/year: 2,275,1954
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 1 mg/kg
- TOXIC EFFECTS :
- Gastrointestinal - other changes Blood - leukopenia Blood - other changes
- REFERENCE :
- CCSUBJ Cancer Chemotherapy Reports, Part 2. (Washington, DC) V.1-5, 1964-75. For publisher information, see CTRRDO. Volume(issue)/page/year: 2,201,1965
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Primate - monkey
- DOSE/DURATION :
- 1 mg/kg
- TOXIC EFFECTS :
- Blood - leukopenia Blood - other changes
- REFERENCE :
- CCSUBJ Cancer Chemotherapy Reports, Part 2. (Washington, DC) V.1-5, 1964-75. For publisher information, see CTRRDO. Volume(issue)/page/year: 2,201,1965