10H-Phenothiazine-10-ethanaminium,N,N,N,a-tetramethyl-, iodide (1:1)

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Names

[ Name ]:
10H-Phenothiazine-10-ethanaminium,N,N,N,a-tetramethyl-, iodide (1:1)

[Synonym ]:
Trimethylammonium-isopropyl-phenthiazin jodid
Promethazin methoiodid
Promethazin-Methyliodid
Promethazine methiodide
Thiazinamium iodide
Promethazinum-methoiodide

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₈H₂₃IN₂S

[ Molecular Weight ]:
426.35800

[ Exact Mass ]:
426.06300

[ PSA ]:
28.54000

[ LogP ]:
1.45300

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: BR8140000

CHEMICAL NAME :: Ammonium, (1-methyl-2-(phenothiazin-10-yl)ethyl)trimethyl-, iodide

CAS REGISTRY NUMBER :: 26212-80-6

LAST UPDATED :: 199203

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C18-H23-N2-S.I

MOLECULAR WEIGHT :: 426.39

WISWESSER LINE NOTATION :: T C666 BN ISJ B1Y1&K1&1&1 &Q &I

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 10 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 120,450,1959

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 11 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 120,450,1959

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 6 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 120,450,1959

Related Compounds

N-tert-butyl-1-(6-methylpyrimidin-4-yl)pyrrolidine-3-carboxamide
N-tert-butyl-1-(5,6-dimethylpyrimidin-4-yl)pyrrolidine-3-carboxamide
N-tert-butyl-1-(6-ethylpyrimidin-4-yl)pyrrolidine-3-carboxamide
N-tert-butyl-1-(6-cyclopropylpyrimidin-4-yl)pyrrolidine-3-carboxamide
N-tert-butyl-1-(6-methoxypyrimidin-4-yl)pyrrolidine-3-carboxamide
N-tert-butyl-1-(5-methoxypyrimidin-2-yl)pyrrolidine-3-carboxamide
N-cyclopropyl-4-(5-fluoropyrimidin-2-yl)morpholine-2-carboxamide
4-(5-chloropyrimidin-2-yl)-N-cyclopropylmorpholine-2-carboxamide
N-tert-butyl-1-[5-cyano-2-(methylsulfanyl)pyrimidin-4-yl]pyrrolidine-3-carboxamide
N-tert-butyl-1-[(pyridin-2-yl)methyl]pyrrolidine-3-carboxamide

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