10H-Phenothiazine-10-ethanaminium,N,N,N,a-tetramethyl-, iodide (1:1)

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Names

[ CAS No. ]:
26212-80-6

[ Name ]:
10H-Phenothiazine-10-ethanaminium,N,N,N,a-tetramethyl-, iodide (1:1)

[Synonym ]:
Trimethylammonium-isopropyl-phenthiazin jodid
Promethazin methoiodid
Promethazin-Methyliodid
Promethazine methiodide
Thiazinamium iodide
Promethazinum-methoiodide

Chemical & Physical Properties

[ Molecular Formula ]:
C18H23IN2S

[ Molecular Weight ]:
426.35800

[ Exact Mass ]:
426.06300

[ PSA ]:
28.54000

[ LogP ]:
1.45300

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
BR8140000
CHEMICAL NAME :
Ammonium, (1-methyl-2-(phenothiazin-10-yl)ethyl)trimethyl-, iodide
CAS REGISTRY NUMBER :
26212-80-6
LAST UPDATED :
199203
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C18-H23-N2-S.I
MOLECULAR WEIGHT :
426.39
WISWESSER LINE NOTATION :
T C666 BN ISJ B1Y1&K1&1&1 &Q &I

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
10 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 120,450,1959
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
11 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 120,450,1959
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
6 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 120,450,1959

Related Compounds

  • Methyl 2-[3-chloro-2-oxo-5-(trifluoromethyl)-1,2-dihydropyridin-1-yl]acetate
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide