tri-o-Tolyl phosphite

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Names

[ CAS No. ]:
2622-08-4

[ Name ]:
tri-o-Tolyl phosphite

[Synonym ]:
Tri-o-cresyl Phosphite
Tri-o-tolyl phosphite
Phosphorous Acid Tri-o-cresyl Ester
MFCD00014911
Tris(2-methylphenyl) Phosphite
TRI-2-TOLYLPHOSPHITE
EINECS 220-068-7
Phosphorous Acid Tri-o-tolyl Ester
Phosphorous Acid Tris(2-methylphenyl) Ester

Chemical & Physical Properties

[ Boiling Point ]:
200-202°C/2.4-2.6mm

[ Molecular Formula ]:
C21H21O3P

[ Molecular Weight ]:
352.36300

[ Flash Point ]:
200-202°C/2.4-2.6mm

[ Exact Mass ]:
352.12300

[ PSA ]:
41.28000

[ LogP ]:
6.37550

[ Vapour Pressure ]:
6.01E-14mmHg at 25°C

[ Storage condition ]:
Refrigerator

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TH1050000
CHEMICAL NAME :
Phosphorous acid, tri-o-cresyl ester
CAS REGISTRY NUMBER :
2622-08-4
LAST UPDATED :
199409
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C21-H21-O6-P
MOLECULAR WEIGHT :
400.39
WISWESSER LINE NOTATION :
QR B1OPO1R BQ&O1R BQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
10 gm/kg
TOXIC EFFECTS :
Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - tremor Behavioral - muscle weakness
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 49,78,1933
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - chicken
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - tremor Behavioral - muscle weakness
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 49,78,1933 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - chicken
DOSE/DURATION :
900 mg/kg/90D-I
TOXIC EFFECTS :
Spinal Cord - other degenerative changes Behavioral - ataxia Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 53,150,1980

Safety Information

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
26-36

[ RTECS ]:
TH1050000

[ HS Code ]:
2920901900

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2920901900

[ Summary ]:
2920901900 VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Related Compounds

  • Tri-o-tolyl Phosphite
  • tri(o-tolyl)phosphine sulphide
  • Chloro[tri(o-tolyl)phosphine]gold(I)
  • 1,3,5-tri-o-tolyl-2,4,6-trichloro borazine
  • N,N',N''-tri-o-tolyl-phosphamide
  • Tris(2-methylphenyl) phosphate
  • 3H-1,2,4-Triazol-3-one,4-(2-chlorophenyl)-2,4-dihydro-
  • 3-(5-Oxo-1,5-dihydro-[1,2,4]triazol-4-yl)-benzonitrile
  • N-benzyl-2-[3-(4-fluoro-2-methoxyphenyl)-6-oxopyridazin-1(6H)-yl]-N-methylacetamide
  • 2-[3-(4-methoxyphenyl)-6-oxopyridazin-1(6H)-yl]-N-[(2E)-5-(propan-2-yl)-1,3,4-thiadiazol-2(3H)-ylidene]acetamide
  • N-(bicyclo[2.2.1]hept-5-en-2-ylmethyl)-1-methyl-5-(1H-pyrrol-1-yl)-1H-pyrazole-4-carboxamide
  • 4-(3,4-Dichlorophenyl)-6-(1H-imidazol-1-yl)pyrimidine
  • 6-(4-fluoro-2-methoxyphenyl)-2-[2-oxo-2-(2-phenylmorpholin-4-yl)ethyl]pyridazin-3(2H)-one
  • N-cycloheptyl-2-[6-oxo-3-(4-phenylpiperazin-1-yl)pyridazin-1(6H)-yl]acetamide
  • N-(1,3-benzodioxol-5-yl)-2-([1,2,4]triazolo[4,3-b]pyridazin-6-ylsulfanyl)acetamide
  • 4-benzyl-N-[2-oxo-2-(pyridin-3-ylamino)ethyl]piperazine-1-carboxamide
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