6-Aminochrysene
Suppliers
Names
[ CAS No. ]:
2642-98-0
[ Name ]:
6-Aminochrysene
[Synonym ]:
Chrysen-6-ylamine
6-Amino-chrysen
Chrysen-6-ylamin
6-AMINOCHRYSENE
Chrysenex
Chrysen-6-amine
6-Amc
Chrysonex
6-chrysenylamine
6-Chrysenamine
MFCD00003699
chrysene-6-ylamine
EINECS 220-149-7
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Boiling Point ]:
501.2±19.0 °C at 760 mmHg
[ Melting Point ]:
209-211 °C(lit.)
[ Molecular Formula ]:
C18H13N
[ Molecular Weight ]:
243.303
[ Flash Point ]:
286.9±16.8 °C
[ Exact Mass ]:
243.104797
[ PSA ]:
26.02000
[ LogP ]:
4.63
[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C
[ Index of Refraction ]:
1.814
[ Storage condition ]:
2-8°C
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- GC0500000
- CHEMICAL NAME :
- 6-Chrysenamine
- CAS REGISTRY NUMBER :
- 2642-98-0
- BEILSTEIN REFERENCE NO. :
- 2114213
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 14
- MOLECULAR FORMULA :
- C18-H13-N
- MOLECULAR WEIGHT :
- 243.32
- WISWESSER LINE NOTATION :
- L E6 B666J MZ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 9504 mg/kg/36D-C
- TOXIC EFFECTS :
- Cardiac - changes in heart weight Liver - changes in liver weight Nutritional and Gross Metabolic - weight loss or decreased weight gain
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1100 gm/kg/39W-I
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application
MUTATION DATA
- TYPE OF TEST :
- Mutation in mammalian somatic cells
- TEST SYSTEM :
- Rodent - hamster Ovary
- DOSE/DURATION :
- 50 mg/L
- REFERENCE :
- JTEHD6 Journal of Toxicology and Environmental Health. (Hemisphere Pub., 1025 Vermont Ave., NW, Washington, DC 20005) V.1- 1975/76- Volume(issue)/page/year: 13,531,1984
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xn: Harmful;
[ Risk Phrases ]:
22
[ Safety Phrases ]:
S45-S36/37/39-S26
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
GC0500000
[ HS Code ]:
2921499090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2921499090
[ Summary ]:
2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
Articles
Carcinogenesis 20(6) , 1079-83, (1999)
Human NAT1 and NAT2 genes were subcloned into pACYC184 vector and the plasmids thus obtained were introduced into Salmonella typhimurium O-acetyltransferase-deficient strain NM6000 (TA1538/1, 8-DNP/pS...
Toxicology 29(4) , 345-56, (1984)
By microspectrofluorimetry on single living cells (murine fibroblasts 3T3), we have obtained monoexponential decreases of fluorescence intensity for benzo[a]pyrene (B[a]P) and 6-aminochrysene (6a-chry...
J. Chromatogr. A. 354 , 442-8, (1986)