SB 415286

Suppliers

Names

[ Name ]:
SB 415286

[Synonym ]:
1H-Pyrrole-2,5-dione, 3-[(3-chloro-4-hydroxyphenyl)amino]-4-(2-nitrophenyl)-
3-[(3-Chloro-4-hydroxyphenyl)amino]-4-(2-nitrophenyl)-1H-pyrrol-2,5-dione
Tocris-1617
3-(3-chloro-4-hydroxyphenylamino)-4-(2-nitrophenyl)-1H-pyrrole-2,5-dione
3-[(3-Chloro-4-hydroxyphenyl)amino]-4-(2-nitrophenyl)-1H-pyrrole-2,5-dione
MFCD04039789
SB 415286

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
595.8±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₆H₁₀ClN₃O₅

[ Molecular Weight ]:
359.721

[ Flash Point ]:
314.1±30.1 °C

[ Exact Mass ]:
359.030884

[ PSA ]:
124.25000

[ LogP ]:
2.06

[ Appearance of Characters ]:
yellow to orange

[ Vapour Pressure ]:
0.0±1.7 mmHg at 25°C

[ Index of Refraction ]:
1.746

[ Storage condition ]:
−20°C

[ Water Solubility ]:
DMSO: 16 mg/mL

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

The antimicrobial protein S100A7/psoriasin enhances the expression of keratinocyte differentiation markers and strengthens the skin's tight junction barrier.

Br. J. Dermatol. 171(4) , 742-53, (2014)

S100A7/psoriasin is a member of the S100 protein family and is encoded in the epidermal differentiation complex, which contains genes for markers of epidermal differentiation. S100A7/psoriasin is over...

Inactivation of glycogen synthase kinase 3 promotes axonal growth and recovery in the CNS.

J. Neurosci. 28(36) , 8914-28, (2008)

Axonal regeneration is minimal after CNS injuries in adult mammals and medical treatments to recover neurological deficits caused by axon disconnection are extremely limited. The failure of axonal elo...

Reduction of experimental colitis in the rat by inhibitors of glycogen synthase kinase-3beta.

Br. J. Pharmacol. 147(5) , 575-82, (2006)

The effects of the inhibitors of glycogen synthase kinase-3beta (GSK-3beta), TDZD-8 and SB 415286, which can substantially reduce the systemic inflammation associated with endotoxic shock in vivo, hav...