N4-Benzoylcytosine

Suppliers

Names

[ Name ]:
N4-Benzoylcytosine

[Synonym ]:
N-(2-oxohydropyrimidin-4-yl)benzamide
N4-Benzoylcytosine
N6-benzoylcytosine
N3-benzoylcytosine
N-(2-Oxo-1,2-dihydro-4-pyrimidinyl)benzamide
N-(2-Oxo-1,2-dihydropyrimidin-4-yl)benzamide
MFCD00239434
N-(1,2-dihydro-2-oxopyrimidin-4-yl)-benzamide
N4-Benzoyl Cytosine
N-benzoylcytosine
Benzamide, N-(1,2-dihydro-2-oxo-4-pyrimidinyl)-
N-(2-Oxo-2,3-dihydropyrimidin-4-yl)benzamide
N4-Bz-cytosine

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Melting Point ]:
>300 °C (dec.)(lit.)

[ Molecular Formula ]:
C₁₁H₉N₃O₂

[ Molecular Weight ]:
215.208

[ Exact Mass ]:
215.069473

[ PSA ]:
74.85000

[ LogP ]:
0.42

[ Index of Refraction ]:
1.652

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315-H319-H332-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R20/22;R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

cytosine
Benzoyl chloride
cytosine monohydrate
Benzoic anhydride
N(4)-benzoyl-2',3'-dideoxy-2',3'-didehydrocytidine

DownStream

Cytidine, N-benzoyl-,2',3',5'-tribenzoate (7CI,9CI)
N4-Bz-2'-OMe-rC
DIETHYL (((1-(4-BENZAMIDO-2-OXOPYRIMIDIN-1(2H)-YL)-3-HYDROXYPROPAN-2-YL)OXY)METHYL)PHOSPHONATE
(S)-(((1-(4-BENZAMIDO-2-OXOPYRIMIDIN-1(2H)-YL)-3-HYDROXYPROPAN-2-YL)OXY)METHYL)PHOSPHONIC ACID
N-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)thiolan-2-yl]-2-oxopyrimidin-4-yl]benzamide
Benzamide, N-[1,2-dihydro-2-oxo-1-(2-propenyl)-4-pyrimidinyl]- (9CI)
(2'R)-N-Benzoyl-2'-deoxy-2'-fluoro-2'-methylcytidine 3',5'-dibenzoate
N-(2-trimethylsilyloxypyrimidin-4-yl)benzamide
N-trimethylsilyl-N-(2-trimethylsilyloxypyrimidin-4-yl)benzamide

Articles

Synthesis and biological evaluation of 3'-C-ethynyl and 3'-C-(1,4-disubstituted-1,2,3-triazolo) double-headed pyranonucleosides.

Med. Chem. 8(3) , 320-9, (2012)

A novel series of 3'-C-ethynyl and 3'-C-(1,4-disubstituted-1,2,3-triazolo) double-headed pyranonucleosides has been designed and synthesized. Reaction of 3-keto glucoside 1 with ethynyl magnesium brom...

Nucleosides and nucleotides. 232. Synthesis of 2'-C-methyl-4'-thiocytidine: unexpected anomerization of the 2'-keto-4'-thionucleoside precursor.

Nucleosides Nucleotides Nucleic Acids 24(10-12) , 1789-800, (2005)

The synthesis of 2'-C-methyl-4'-thiocytidine (16) is described. Since the 2'-keto-4'-thiocytidine derivative 2beta unexpectedly isomerized to 2alpha and the methylation of 2beta proceeded predominantl...

Synthesis and anti-HIV and anti-HBV activities of 2'-fluoro-2', 3'-unsaturated L-nucleosides.

J. Med. Chem. 42(7) , 1320-8, (1999)

The synthesis of L-nucleoside analogues containing 2'-vinylic fluoride was accomplished by direct condensation method, and their anti-HIV and anti-HBV activities were evaluated in vitro. The key inter...

5-fluoro-N4-benzoylcytosine
5-methyl-N4-benzoylcytosine
N4-benzoyl-bis(trimethylsilyl)cytosine
N4-(3-Chloro-4-fluorophenyl)-7-[(7-methyl-7-azaspiro[3.5]non-2-yl)methoxy]-4,6-quinazolinediamine
N4-acetyl-1-<2'-deoxy-3',5'-di-O-acetyl-β-D-ribofyranosyl>cytosine
N4-SUCCINYLSULFATHIAZOLE MONOHYDRATE
2-(3,4-dimethoxyphenyl)-N-(7-methyl-5-oxo-5H-thiazolo[3,2-a]pyrimidin-6-yl)acetamide
2-furyl-N-{[1-(2-methylprop-2-enyl)benzimidazol-2-yl]ethyl}carboxamide
4-iodo-N-(7-methyl-5-oxo-5H-thiazolo[3,2-a]pyrimidin-6-yl)benzamide
4-methyl-N-(7-methyl-5-oxo-5H-thiazolo[3,2-a]pyrimidin-6-yl)-2-phenylthiazole-5-carboxamide
2-furyl-N-({1-[2-(2-prop-2-enylphenoxy)ethyl]benzimidazol-2-yl}ethyl)carboxami de
N-[1-(1-allyl-1H-benzimidazol-2-yl)ethyl]-2-furamide
N-{7-methyl-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-6-yl}oxolane-2-carboxamide
N-(3,7-dimethyl-5-oxo-5H-thiazolo[3,2-a]pyrimidin-6-yl)-3,3-dimethylbutanamide
4-{1-[2-(4-chlorophenoxy)ethyl]-1H-1,3-benzodiazol-2-yl}-1-[(4-fluorophenyl)methyl]pyrrolidin-2-one
ethyl 2-((3,7-dimethyl-5-oxo-5H-thiazolo[3,2-a]pyrimidin-6-yl)amino)-2-oxoacetate

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