clofibride
Suppliers
Names
[ CAS No. ]:
26717-47-5
[ Name ]:
clofibride
[Synonym ]:
Butyramide,N-dimethyl-4-(p-chlorophenoxyisobutyrate)
Clofibride
Clofibrida [INN-Spanish]
N-Dimethyl-4-(p-chlorophenoxyisobutyrate)butyramide
MG 46
EINECS 247-912-7
Lipenan
3-dimethylcarbamoylpropyl 2-(4-chlorophenoxy)-2-methylpropionate
Clofibridum [INN-Latin]
Chemical & Physical Properties
[ Density]:
1.163g/cm3
[ Boiling Point ]:
448.7ºC at 760mmHg
[ Molecular Formula ]:
C16H22ClNO4
[ Molecular Weight ]:
327.80300
[ Flash Point ]:
225.2ºC
[ Exact Mass ]:
327.12400
[ PSA ]:
55.84000
[ LogP ]:
2.90900
[ Vapour Pressure ]:
3.04E-08mmHg at 25°C
[ Index of Refraction ]:
1.515
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UE9458000
- CHEMICAL NAME :
- Propionic acid, 2-(p-chlorophenoxy)-2-methyl-, ester with 4-hydroxy-N,N-dimethylbutyramide
- CAS REGISTRY NUMBER :
- 26717-47-5
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C16-H22-Cl-N-O4
- MOLECULAR WEIGHT :
- 327.84
- WISWESSER LINE NOTATION :
- GR DOX1&1&VO3VN1&1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2485 mg/kg
- TOXIC EFFECTS :
- Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - cyanosis Lungs, Thorax, or Respiration - respiratory depression
- REFERENCE :
- JETOAS Journal Europeen de Toxicologie. (Paris, France) V.1-6, 1968-72. For publisher information, see TOERD9. Volume(issue)/page/year: 5,239,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1175 mg/kg
- TOXIC EFFECTS :
- Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - cyanosis Lungs, Thorax, or Respiration - respiratory depression
- REFERENCE :
- JETOAS Journal Europeen de Toxicologie. (Paris, France) V.1-6, 1968-72. For publisher information, see TOERD9. Volume(issue)/page/year: 5,239,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1080 mg/kg
- TOXIC EFFECTS :
- Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - cyanosis Lungs, Thorax, or Respiration - respiratory depression
- REFERENCE :
- JETOAS Journal Europeen de Toxicologie. (Paris, France) V.1-6, 1968-72. For publisher information, see TOERD9. Volume(issue)/page/year: 5,239,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 960 mg/kg
- TOXIC EFFECTS :
- Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - cyanosis Lungs, Thorax, or Respiration - respiratory depression
- REFERENCE :
- JETOAS Journal Europeen de Toxicologie. (Paris, France) V.1-6, 1968-72. For publisher information, see TOERD9. Volume(issue)/page/year: 5,239,1972 ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 14 gm/kg
- SEX/DURATION :
- male 7 day(s) pre-mating female 7 day(s) pre-mating female 1-22 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Newborn - stillbirth
- REFERENCE :
- JETOAS Journal Europeen de Toxicologie. (Paris, France) V.1-6, 1968-72. For publisher information, see TOERD9. Volume(issue)/page/year: 5,239,1972
Safety Information
[ HS Code ]:
2924299090
Customs
[ HS Code ]: 2924299090
[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%