S-(2-ethylsulphinyl-1-methylethyl)-O,O-dimethyl phosphorothioate

Suppliers

Names

[ CAS No. ]:
2674-91-1

[ Name ]:
S-(2-ethylsulphinyl-1-methylethyl)-O,O-dimethyl phosphorothioate

[Synonym ]:
S-[2-(ethylsulfinyl)-1-methylethyl] O,O-dimethyl phosphorothioate
Thiophosphorsaeure-S-(2-aethansulfinyl-1-methyl-aethylester)-O,O'-dimethylester
Oxyphionfos
Estox
Caswell No. 366
Oxydeprofos
2-dimethoxyphosphorylsulfanyl-1-ethylsulfinylpropane
Metasystox-S
S-[(1RS)-2-(ethylsulfinyl)-1-methylethyl] O,O-dimethyl phosphorothioate
S-[(2RS)-1-(ethanesulfinyl)propan-2-yl] O,O-dimethyl phosphorothioate
Thiometan
EINECS 220-221-8
Oxydeprofos [ISO]
ESP

Chemical & Physical Properties

[ Density]:
1.271g/cm3

[ Boiling Point ]:
382.8ºC at 760mmHg

[ Molecular Formula ]:
C7H17O4PS2

[ Molecular Weight ]:
260.31100

[ Flash Point ]:
185.3ºC

[ Exact Mass ]:
260.03100

[ PSA ]:
106.92000

[ LogP ]:
3.14330

[ Vapour Pressure ]:
1.02E-05mmHg at 25°C

[ Index of Refraction ]:
1.514

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TG1575000
CHEMICAL NAME :
Phosphorothioic acid, S-(2-(ethylsulfinyl)-1-methylethyl) O,O-dimethyl ester
CAS REGISTRY NUMBER :
2674-91-1
BEILSTEIN REFERENCE NO. :
1711537
LAST UPDATED :
199612
DATA ITEMS CITED :
17
MOLECULAR FORMULA :
C7-H17-O4-P-S2
MOLECULAR WEIGHT :
260.33
WISWESSER LINE NOTATION :
OS2&1Y1&SPO&O1&O1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
89 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
820 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
27 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
29 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
105 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
58700 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
30 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
24 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
225 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
410 mg/kg/13W-C
TOXIC EFFECTS :
Endocrine - changes in spleen weight Blood - changes in erythrocyte (RBC) count Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1529 mg/kg/2Y-C
TOXIC EFFECTS :
Brain and Coverings - other degenerative changes Blood - other changes Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1095 mg/kg/52W-C
TOXIC EFFECTS :
Liver - changes in liver weight Blood - other changes Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
683 mg/kg/13W-C
TOXIC EFFECTS :
Brain and Coverings - other degenerative changes Blood - other changes Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
50 mg/plate
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 116,185,1983 *** REVIEWS *** TOXICOLOGY REVIEW RREVAH Residue Reviews. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1962- Volume(issue)/page/year: 63,1,1976

Safety Information

[ RIDADR ]:
UN 3018

[ Packaging Group ]:
II

[ Hazard Class ]:
6.1(a)

[ HS Code ]:
2930909061

Customs

[ HS Code ]: 2930909061

[ Summary ]:
2930909061 o,o,o',o'-tetramethyl o,o'-(thiobis(4,1-phenylene)) diphosphorothioate。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:30.0%