2-Methyl-4-Isothiazolin-3-one

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Names

[ CAS No. ]:
2682-20-4

[ Name ]:
2-Methyl-4-Isothiazolin-3-one

[Synonym ]:
METHYLISOTHIAZOLIN
2-Methyl-3(2H)-isothiazolone
2-METHYLISOTHIAZOLINONE
METHYLISOTHIAZOLINE
2-methylisothiazolin-3-one
MFCD00013254
2-Methyl-1,2-thiazol-3(2H)-one
METHYLISOTHIAZDINONE
Skycide 100
KATHONCG
methylisothiazolin-3-one
2-Methylisothiazol-3(2H)-one
Isothiazolone,2-methyl
N-Methylisothiazolone
MI
2-methyl-3-isothiazolone
2-methyl-2H-isothiazol-3-one
2-Methyl-4-Isothiazolin-3-one
3(2H)-Isothiazolone, 2-methyl-
methylisothiazolinone
2-methylisothiazolone
T5SNVJ B1
METHYLISOTHIAZOLONE
EINECS 220-239-6
N-methyl-isothiazole-HCl
MIT
2-Methyl-4-isothiazoline-3-one

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
182.8±23.0 °C at 760 mmHg

[ Melting Point ]:
254-256 °C(lit.)

[ Molecular Formula ]:
C4H5NOS

[ Molecular Weight ]:
115.154

[ Flash Point ]:
64.3±22.6 °C

[ Exact Mass ]:
115.009186

[ PSA ]:
50.24000

[ LogP ]:
0.05

[ Vapour Pressure ]:
0.8±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.589

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NX8157080
CHEMICAL NAME :
3(2H)-Isothiazolone, 2-methyl-
CAS REGISTRY NUMBER :
2682-20-4
LAST UPDATED :
199710

Safety Information

[ Symbol ]:

GHS05, GHS06, GHS09

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H314-H317-H331-H335-H400

[ Precautionary Statements ]:
P261-P273-P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
C:Corrosive

[ Risk Phrases ]:
R20/21/22;R34;R43;R50

[ Safety Phrases ]:
S60-S61-S36/37/39-S26-S24-S45

[ RIDADR ]:
UN 3077 9/PG 3

[ WGK Germany ]:
2

[ RTECS ]:
FE1250000

[ Packaging Group ]:
III

[ Hazard Class ]:
8

[ HS Code ]:
2934100090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • N,N′-Dimethyl-3,3′-dithiodipropionamide
  • 5-(4-methoxybenzoyl)-2-methylisothiazol-3(2H)-one
  • 2-methyl-1,2-thiazolidin-3-one
  • tert-Butyl peroxybenzoate

DownStream

  • 4,5-Dichloro-2-methyl-3(2H)-isothiazolone

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Methylisothiazolinone contact allergy and dose-response relationships.

Contact Dermatitis 64(6) , 330-6, (2011)

Methylisothiazolinone (MI) used alone is a new preservative causing a high prevalence of contact allergy. The eliciting threshold of MI is unknown. The combination of MI and phenoxyethanol enhances th...

Follow-up of the monitored levels of preservative sensitivity in Europe: overview of the years 2001-2008.

Contact Dermatitis 67(5) , 312-4, (2012)

Occupational contact dermatitis in painters: an analysis of patch test data from the Danish Contact Dermatitis Group.

Contact Dermatitis 67(5) , 293-7, (2012)

Painters are among the occupational groups that most commonly experience occupational contact dermatitis, but few investigations exist concerning this occupation.To characterize painters with contact ...


More Articles

Related Compounds

  • 4-chloro-2-methyl-4-isothiazolin-3-one
  • 5-Chloro-2-methyl-4-isothiazolin-3-one
  • 4,5-dichloro-2-methyl-4-isothiazolin-3-one
  • 2-Methyl-4-isothiazolin-3-one calcium chloride
  • 5-Chloro-2-methyl-4-isothiazolin-3-one hydrochloride
  • 5-Chloro-2-methyl-4-isothiazolin-3-one calcium chloride