Cephalotaxine,3-[4-methyl (2R,3S)-2,3-dihydroxy-2-(3-methylbutyl)butanedioate]

Suppliers

Names

[ CAS No. ]:
26833-86-3

[ Name ]:
Cephalotaxine,3-[4-methyl (2R,3S)-2,3-dihydroxy-2-(3-methylbutyl)butanedioate]

[Synonym ]:
iso-harringtonine

Chemical & Physical Properties

[ Density]:
1.35g/cm3

[ Boiling Point ]:
632.5ºC at 760mmHg

[ Melting Point ]:
70.75°C

[ Molecular Formula ]:
C28H37NO9

[ Molecular Weight ]:
531.59500

[ Exact Mass ]:
531.24700

[ PSA ]:
123.99000

[ LogP ]:
1.98440

[ Vapour Pressure ]:
7.21E-17mmHg at 25°C

[ Index of Refraction ]:
1.607

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NR2935500
CHEMICAL NAME :
Isoharringtonine
CAS REGISTRY NUMBER :
26833-86-3
LAST UPDATED :
198909
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C28-H37-N-O9

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
27950 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NCISP* National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program. (Bethesda, MD 20205) Volume(issue)/page/year: JAN1986
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
14600 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JOETD7 Journal of Ethnopharmacology. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1979- Volume(issue)/page/year: 24,1,1988
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
26110 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NCISP* National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program. (Bethesda, MD 20205) Volume(issue)/page/year: JAN1986
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
13200 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JOETD7 Journal of Ethnopharmacology. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1979- Volume(issue)/page/year: 24,1,1988

Related Compounds

  • (5-Fluoro-1-tetrahydropyran-2-YL-indazol-4-YL)boronic acid
  • Ethyl N-(4-cyano-2-methyl-5-oxazolyl)ethanimidate
  • 4-Chloro-3-(2,2,2-trifluoroacetamido)thiophene-2-carboxylic acid
  • Di-mu-chlorooctachlorodivanadate(2-)
  • 7-Amino-4-bromo-2-phenyl-2,4,6-cycloheptatrien-1-one
  • 4-Chloro-2-(3-piperidinyl)-3H-imidazo[4,5-c]pyridine
  • 5-Thiazolamine, 4-(4-fluoro-1-methyl-1H-indol-2-yl)-
  • 3-[2-(Dimethylamino)-1,3-thiazol-5-yl]-2,2-dimethylpropanoic acid
  • 4-bromo-N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-3-propoxybenzene-1-sulfonamide
  • 5-tert-butyl-N-(2,4-dimethylphenyl)-2-propoxybenzene-1-sulfonamide
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.